日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders

一种靶向eIF4E内部结合位点的联苯抑制剂可用于设计细胞可渗透的PROTAC降解剂。

Fischer, Patrick D; Papadopoulos, Evangelos; Dempersmier, Jon M; Wang, Zi-Fu; Nowak, Radosław P; Donovan, Katherine A; Kalabathula, Joann; Gorgulla, Christoph; Junghanns, Pierre P M; Kabha, Eihab; Dimitrakakis, Nikolaos; Petrov, Ognyan I; Mitsiades, Constantine; Ducho, Christian; Gelev, Vladimir; Fischer, Eric S; Wagner, Gerhard; Arthanari, Haribabu

Dot1l interacts with Zc3h10 to activate Ucp1 and other thermogenic genes

Dot1l 与 Zc3h10 相互作用激活 Ucp1 和其他产热基因

Danielle Yi #, Hai P Nguyen #, Jennie Dinh, Jose A Viscarra, Ying Xie, Frances Lin, Madeleine Zhu, Jon M Dempersmier, Yuhui Wang, Hei Sook Sul

Zc3h10 Acts as a Transcription Factor and Is Phosphorylated to Activate the Thermogenic Program

Zc3h10 充当转录因子,并被磷酸化以激活产热程序

Danielle Yi, Jon M Dempersmier, Hai P Nguyen, Jose A Viscarra, Jennie Dinh, Chihiro Tabuchi, Yuhui Wang, Hei Sook Sul

Actomyosin-Mediated Tension Orchestrates Uncoupled Respiration in Adipose Tissues

肌动球蛋白介导的张力协调脂肪组织中的非偶联呼吸

Kevin M Tharp, Michael S Kang, Greg A Timblin, Jon Dempersmier, Garret E Dempsey, Peter-James H Zushin, Jaime Benavides, Catherine Choi, Catherine X Li, Amit K Jha, Shingo Kajimura, Kevin E Healy, Hei Sook Sul, Kaoru Saijo, Sanjay Kumar, Andreas Stahl

Epigenetic Regulation of the Thermogenic Adipose Program

脂肪组织产热程序的表观遗传调控

Sambeat, Audrey; Gulyaeva, Olga; Dempersmier, Jon; Sul, Hei Sook

Cold-inducible Zfp516 activates UCP1 transcription to promote browning of white fat and development of brown fat

冷诱导的 Zfp516 激活 UCP1 转录,促进白色脂肪褐变和棕色脂肪的形成

Dempersmier, Jon; Sambeat, Audrey; Gulyaeva, Olga; Paul, Sarah M; Hudak, Carolyn S S; Raposo, Helena F; Kwan, Hiu-Yee; Kang, Chulho; Wong, Roger H F; Sul, Hei Sook