A Randomized, Double-Blind, Biomarker-Selected, Phase II Clinical Trial of Maintenance Poly ADP-Ribose Polymerase Inhibition With Rucaparib Following Chemotherapy for Metastatic Urothelial Carcinoma
一项随机、双盲、生物标志物筛选的II期临床试验,旨在评估化疗后使用Rucaparib维持聚ADP核糖聚合酶抑制治疗转移性尿路上皮癌的疗效。
期刊:Journal of Clinical Oncology
影响因子:41.9
doi:10.1200/JCO.22.00405
Crabb, Simon J; Hussain, Syed; Soulis, Eileen; Hinsley, Samantha; Dempsey, Laura; Trevethan, Avril; Song, YeePei; Barber, Jim; Frew, John; Gale, Joanna; Faust, Guy; Brock, Susannah; McGovern, Ursula; Parikh, Omi; Enting, Deborah; Sundar, Santhanam; Ratnayake, Gihan; Lees, Kathryn; Birtle, Alison J; Powles, Thomas; Jones, Robert J