日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Phase Ib Dose-Escalation Study of Encorafenib and Cetuximab with or without Alpelisib in Metastatic BRAF-Mutant Colorectal Cancer

一项针对转移性BRAF突变型结直肠癌的恩科拉非尼联合西妥昔单抗(加或不加阿培利西布)的Ib期剂量递增研究

van Geel, Robin M J M; Tabernero, Josep; Elez, Elena; Bendell, Johanna C; Spreafico, Anna; Schuler, Martin; Yoshino, Takayuki; Delord, Jean-Pierre; Yamada, Yasuhide; Lolkema, Martijn P; Faris, Jason E; Eskens, Ferry A L M; Sharma, Sunil; Yaeger, Rona; Lenz, Heinz-Josef; Wainberg, Zev A; Avsar, Emin; Chatterjee, Arkendu; Jaeger, Savina; Tan, Eugene; Maharry, Kati; Demuth, Tim; Schellens, Jan H M

Phase I Study Evaluating WEE1 Inhibitor AZD1775 As Monotherapy and in Combination With Gemcitabine, Cisplatin, or Carboplatin in Patients With Advanced Solid Tumors

一项评估 WEE1 抑制剂 AZD1775 单药治疗以及与吉西他滨、顺铂或卡铂联合治疗晚期实体瘤患者的 I 期研究

Leijen, Suzanne; van Geel, Robin M J M; Pavlick, Anna C; Tibes, Raoul; Rosen, Lee; Razak, Albiruni R Abdul; Lam, Raymond; Demuth, Tim; Rose, Shelonitda; Lee, Mark A; Freshwater, Tomoko; Shumway, Stuart; Liang, Li Wen; Oza, Amit M; Schellens, Jan H M; Shapiro, Geoffrey I

Phase I trial of MK-0752 in children with refractory CNS malignancies: a pediatric brain tumor consortium study

MK-0752治疗难治性中枢神经系统恶性肿瘤患儿的I期临床试验:一项儿科脑肿瘤联盟研究

Fouladi, Maryam; Stewart, Clinton F; Olson, James; Wagner, Lars M; Onar-Thomas, Arzu; Kocak, Mehmet; Packer, Roger J; Goldman, Stewart; Gururangan, Sridharan; Gajjar, Amar; Demuth, Tim; Kun, Larry E; Boyett, James M; Gilbertson, Richard J

Targeting radiation-induced G(2) checkpoint activation with the Wee-1 inhibitor MK-1775 in glioblastoma cell lines

利用 Wee-1 抑制剂 MK-1775 靶向胶质母细胞瘤细胞系中辐射诱导的 G(2) 检查点激活

Sarcar, Bhaswati; Kahali, Soumen; Prabhu, Antony H; Shumway, Stuart D; Xu, Yang; Demuth, Tim; Chinnaiyan, Prakash

The phosphorylation of ephrin-B2 ligand promotes glioma cell migration and invasion.

Ephrin-B2 配体的磷酸化促进神经胶质瘤细胞的迁移和侵袭

Nakada Mitsutoshi, Anderson Eric M, Demuth Tim, Nakada Satoko, Reavie Linsey B, Drake Kelsey L, Hoelzinger Dominique B, Berens Michael E