PD-L1 on ex-vivo Expanded Toll-like-receptor-Bregs Prevents Allograft Rejection by Breg Viability Promotion, CD4(+)T Effector Cell Suppression, and Tregs Induction
体外扩增的 Toll 样受体调节性 B 细胞上的 PD-L1 通过促进 Breg 细胞活力、抑制 CD4(+)T 效应细胞和诱导 Treg 细胞来预防同种异体移植排斥反应。
期刊:American Journal of Transplantation
影响因子:8.2
doi:10.1016/j.ajt.2025.08.031
Liao, Minxue; Liu, Jing; Lee, Kang Mi; Tomofuji, Katsuhiro; Tanimine, Naoki; Markmann, Caroline; Deng, Kevin; Matheson, Rudy; Yu, Matthew; Bourgeois, Olivia; Wei, Liang; Kharga, Anil; Yeh, Heidi; Leguern, Christian; Deng, Shaoping; Lei, Ji; Borges, Thiago J; Riella, Leonardo V; Zhao, Gaoping; Markmann, James F
T细胞
信号转导
免疫排斥
PD-L1
Treg
细胞生物学
CD4
