Deng Xufang相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Structure-Based Design of Covalent SARS-CoV‑2 Main Protease Inhibitors Targeting the Nirmatrelvir-Resistant E166 Mutants

基于结构的共价SARS-CoV-2主蛋白酶抑制剂设计，靶向耐尼马替利韦的E166突变体

影响因子:8.7

doi:10.1021/jacsau.5c01178

Cai, Zhengjun; Kohaal, Navita; Georgiou, Kyriakos; Liang, Xueying; Chi, Xiang; Tan, Haozhou; Tan, Bin; Li, Kan; Fan, Guangjin; Lambrinidis, George; Kolocouris, Antonios; Deng, Xufang; Chen, Yu; Wang, Jun

发表日期：2026

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Characterization of the Cross-Resistance of SARS-CoVâ2 Main Protease Inhibitors, Ibuzatrelvir, Ensitrelvir, and Nirmatrelvir.

SARS-CoV-2 主要蛋白酶抑制剂伊布扎替韦、恩西替韦和尼马替韦的交叉耐药性特征。

期刊:ACS Pharmacology and Translational Science

影响因子:3.7

doi:10.1021/acsptsci.5c00681

Tan Haozhou, Chi Xiang, Deng Xufang, Wang Jun

发表日期：2026

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Identification of naturally occurring drug-resistant mutations of SARS-CoV-2 papain-like protease.

SARS-CoV-2木瓜蛋白酶样蛋白酶天然耐药突变的鉴定

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-59922-9

Tan Haozhou, Zhang Qianru, Georgiou Kyriakos, Zhang Siyu, Li Kan, Lambrinidis George, Kolocouris Antonios, Deng Xufang, Wang Jun

发表日期：2025

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Single-Cell RNA-Seq Identifies Immune Remodeling in Lungs of β-Carotene Oxygenase 2 Knockout Mice with Improved Antiviral Response

单细胞RNA测序揭示β-胡萝卜素加氧酶2敲除小鼠肺部免疫重塑及其抗病毒反应增强

期刊:Nutrients

doi:10.3390/nu17213329

Tang, Yashu; Lin, William; Chi, Xiang; Chen, Huimin; Lin, Dingbo; Chowanadisai, Winyoo; Deng, Xufang; Lu, Peiran

免疫/内分泌

细胞生物学

发表日期：2025

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Correction: Identification of acrylamide-based covalent inhibitors of SARS-CoV-2 (SCoV-2) Nsp15 using high-throughput screening and machine learning

更正：利用高通量筛选和机器学习鉴定基于丙烯酰胺的SARS-CoV-2 (SCoV-2) Nsp15共价抑制剂

期刊:RSC Advances

影响因子:4.6

doi:10.1039/d5ra90098k

Bajaj, Teena; Mosavati, Babak; Zhang, Lydia H; Parsa, Mohammad S; Wang, Huanchen; Kerek, Evan M; Liang, Xueying; Tabatabaei Dakhili, Seyed Amir; Wehri, Eddie; Guo, Silin; Desai, Rushil N; Orr, Lauren M; Mofrad, Mohammad R K; Schaletzky, Julia; Ussher, John R; Deng, Xufang; Stanley, Robin; Hubbard, Basil P; Nomura, Daniel K; Murthy, Niren

发表日期：2025

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Identification of acrylamide-based covalent inhibitors of SARS-CoV-2 (SCoV-2) Nsp15 using high-throughput screening and machine learning.

利用高通量筛选和机器学习鉴定 SARS-CoV-2 (SCoV-2) Nsp15 的丙烯酰胺基共价抑制剂

期刊:RSC Advances

影响因子:4.6

doi:10.1039/d4ra06955b

Bajaj Teena, Mosavati Babak, Zhang Lydia H, Parsa Mohammad S, Wang Huanchen, Kerek Evan M, Liang Xueying, Tabatabaei Dakhili Seyed Amir, Wehri Eddie, Guo Silin, Desai Rushil N, Orr Lauren M, Mofrad Mohammad R K, Schaletzky Julia, Ussher John R, Deng Xufang, Stanley Robin, Hubbard Basil P, Nomura Daniel K, Murthy Niren

发表日期：2025

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Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model

设计一种在小鼠模型中具有抗病毒功效的SARS-CoV-2木瓜蛋白酶样蛋白酶抑制剂

影响因子:45.8

doi:10.1126/science.adm9724

Tan, Bin; Zhang, Xiaoming; Ansari, Ahmadullah; Jadhav, Prakash; Tan, Haozhou; Li, Kan; Chopra, Ashima; Ford, Alexandra; Chi, Xiang; Ruiz, Francesc Xavier; Arnold, Eddy; Deng, Xufang; Wang, Jun

发表日期：2024

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Structure-Based Design of Covalent SARS-CoV-2 Papain-like Protease Inhibitors.

基于结构的共价SARS-CoV-2木瓜蛋白酶样蛋白酶抑制剂设计

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.4c01872

Tan Bin, Liang Xueying, Ansari Ahmadullah, Jadhav Prakash, Tan Haozhou, Li Kan, Ruiz Francesc Xavier, Arnold Eddy, Deng Xufang, Wang Jun

发表日期：2024

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Design of SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model

设计一种在小鼠模型中具有抗病毒功效的SARS-CoV-2木瓜蛋白酶样蛋白酶抑制剂

doi:10.1101/2023.12.01.569653

Tan, Bin; Zhang, Xiaoming; Ansari, Ahmadullah; Jadhav, Prakash; Tan, Haozhou; Li, Kan; Chopra, Ashima; Ford, Alexandra; Chi, Xiang; Ruiz, Francesc Xavier; Arnold, Eddy; Deng, Xufang; Wang, Jun

发表日期：2023

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Development and utilization of an infectious clone for porcine deltacoronavirus strain USA/IL/2014/026

猪δ冠状病毒株感染性克隆的开发与利用 USA/IL/2014/026

doi:10.1016/j.virol.2020.11.002

Deng, Xufang; Buckley, Alexandra C; Pillatzki, Angela; Lager, Kelly M; Baker, Susan C; Faaberg, Kay S

发表日期：2021

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