日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

KCC2 activation during postnatal development alleviates long-term deficits in CDKL5-deficient mice

出生后发育过程中KCC2的激活可缓解CDKL5缺陷小鼠的长期功能障碍。

Arshad, Muhammad Nauman; Bope, Christopher; Cho, Noell; Dengler, Jacob S; Ng, Shu Fun Josephine; Smalley, Joshua L; Nishi, Toshiya; Zhong, Zhong; Moss, Stephen J; Davies, Paul A

KCC2 inhibition and neuronal hyperexcitability promote extrinsic apoptosis dependent upon C1q.

KCC2抑制和神经元过度兴奋促进依赖于C1q的外源性细胞凋亡

Ji Jinglin, Choi Catherine, Bope Christopher E, Dengler Jacob S, Moss Stephen J, Smalley Joshua L

Activation of KCC2 during development alleviates cognitive, behavioral, and neural excitability in adult CDKL5-deficient mice

发育过程中KCC2的激活可减轻成年CDKL5缺陷小鼠的认知、行为和神经兴奋性。

Arshad, Muhammad Nauman; Bope, Christopher; Dengler, Jacob S; Ng, Shu Fun Josephine; Smalley, Joshua; Nishi, Toshiya; Zhong, Zhong; Moss, Stephen J; Davies, Paul A