Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia.
BAX 基因的获得性突变可使急性髓系白血病对 BH3 模拟疗法产生耐药性
期刊:Blood
影响因子:23.1
doi:10.1182/blood.2022016090
Moujalled Donia M, Brown Fiona C, Chua Chong Chyn, Dengler Michael A, Pomilio Giovanna, Anstee Natasha S, Litalien Veronique, Thompson Ella, Morley Thomas, MacRaild Sarah, Tiong Ing S, Morris Rhiannon, Dun Karen, Zordan Adrian, Shah Jaynish, Banquet Sebastien, Halilovic Ensar, Morris Erick, Herold Marco J, Lessene Guillaume, Adams Jerry M, Huang David C S, Roberts Andrew W, Blombery Piers, Wei Andrew H