日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

KRASG12R-Mutant Pancreatic Cancer Features Limited ERK/MAPK Transcriptional Activity and a Distinctive Tumor Microenvironment

KRASG12R突变型胰腺癌具有ERK/MAPK转录活性受限和独特的肿瘤微环境。

期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-25-2630
Burge, Rachel A; Le Roux, Ozgun; Popow, Olesja; Spadafora, Victoria K; Rajesh, Christabelle; Adair, Sara J; Bialousow, Lucas; Murphy, Cailey; Saberi, Samaneh; Vaena, Silvia G; Taquey, Margaret C; Allen, Sarah; Han, Lu; Helke, Kristi L; Sharma, Sudarshana; Ostrowski, Michael C; Guttridge, Denis C; Dincman, Toros A; Bauer, Todd W; Kashatus, David F; McFall, Thomas; Haigis, Kevin M; Hollingsworth, Michael A; Counter, Christopher M; Der, Channing J; Hobbs, G Aaron
肿瘤
肿瘤免疫
MAPK/ERK
胰腺癌
RAS
肿瘤微环境
发表日期：2026
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High-fat diet and obesity each increase tumor cell proliferation and muscle wasting in experimental cancer cachexia

高脂饮食和肥胖均会加剧实验性癌症恶病质中的肿瘤细胞增殖和肌肉萎缩。

期刊:American Journal of Physiology-Cell Physiology
影响因子:4.7
doi:10.1152/ajpcell.00545.2025
Counts, Brittany R; Bonetto, Andrea; Chan, Ho Lam; Au, Ernie D; Jiang, Yanlin; Couch, Marion E; Guttridge, Denis C; Ostrowski, Michael C; Koniaris, Leonidas G; Zimmers, Teresa A
肿瘤
肿瘤免疫
代谢
肥胖
细胞生物学
肿瘤细胞
发表日期：2026
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Screening for Peptides to Bind and Functionally Inhibit SARS-CoV-2 Fusion Peptide Using Mirrored Combinatorial Phage Display and Human Proteomic Phage Display

利用镜像组合噬菌体展示和人蛋白质组噬菌体展示技术筛选能结合并功能性抑制SARS-CoV-2融合肽的肽段。

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules31020282
Pal, Ajay; Roy, Neeladri Sekhar; Angeliadis, Matthew; Madhu, Priyanka; O'Reilly, Sophie; Bera, Indrani; Francois, Nathan; Lynch, Aisling; Gautier, Virginie; Devocelle, Marc; O'Connell, David J; Shields, Denis C
SARS-CoV-2
Human
发表日期：2026
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Randomized Phase II Study of Nab-Paclitaxel and Gemcitabine With or Without Tocilizumab as First-Line Treatment in Advanced Pancreatic Cancer: Survival and Cachexia

一项随机II期研究比较了紫杉醇纳米粒联合吉西他滨（加或不加托珠单抗）作为晚期胰腺癌一线治疗方案的疗效：生存率和恶病质

期刊:Journal of Clinical Oncology
影响因子:41.9
doi:10.1200/JCO.23.01965
Chen, Inna M; Johansen, Julia S; Theile, Susann; Silverman, Libbie M; Pelz, Katherine R; Madsen, Kasper; Dajani, Olav; Lim, Kevin Z M; Lorentzen, Torben; Gaafer, Omnia; Koniaris, Leonidas G; Ferreira, Anna C; Neelon, Brian; Guttridge, Denis C; Ostrowski, Michael C; Zimmers, Teresa A; Nielsen, Dorte
胰腺癌
肿瘤
肿瘤免疫
发表日期：2025
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How to build machine learning models able to extrapolate from standard to modified peptides

如何构建能够从标准肽推断修饰肽的机器学习模型

期刊:Journal of Cheminformatics
影响因子:5.7
doi:10.1186/s13321-025-01115-z
Fernández-Díaz, Raúl; Ochoa, Rodrigo; Hoang, Thanh Lam; Lopez, Vanessa; Shields, Denis C
发表日期：2025
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Relaxation of Shear-Induced Orientation and Textures in Semi-Dilute DNA Solutions

半稀释DNA溶液中剪切诱导取向和纹理的松弛

期刊:Polymers
影响因子:4.9
doi:10.3390/polym17182452
López-Alvarez, Scarlett Elizabeth; Caton, François; Roux, Denis C D; Soltero Martínez, Félix Armando; Scholkopf, Florian; Nallet, Frédéric; Toriz, Guillermo; Saint-Jalmes, Arnaud; Rinaudo, Marguerite; Bravo-Anaya, Lourdes Mónica
发表日期：2025
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Molecular Modelling in Bioactive Peptide Discovery and Characterisation

分子建模在生物活性肽发现和表征中的应用

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom15040524
Agoni, Clement; Fernández-Díaz, Raúl; Timmons, Patrick Brendan; Adelfio, Alessandro; Gómez, Hansel; Shields, Denis C
发表日期：2025
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A Pangenomic Approach to Improve Population Genetics Analysis and Reference Bias in Underrepresented Middle Eastern and Horn of Africa Populations

利用泛基因组学方法改进中东和非洲之角代表性不足人群的群体遗传学分析和参考偏差

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom15040582
Oliva, Adrien; Foare, Rachel; Campbell, Peter; Twine, Natalie A; Bauer, Denis C; Johar, Angad Singh
发表日期：2025
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Modulating the CXCR2 Signaling Axis Using Engineered Chemokine Fusion Proteins to Disrupt Myeloid Cell Infiltration in Pancreatic Cancer

利用工程化趋化因子融合蛋白调节CXCR2信号通路以破坏胰腺癌中的髓系细胞浸润

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom15050645
Benjamin N Christopher ，Lena Golick ，Ashton Basar ，Leticia Reyes ，Reeder M Robinson ，Aaron O Angerstein ，Carsten Krieg ，G Aaron Hobbs ，Denis C Guttridge ，John P O'Bryan ，Nathan G Dolloff
免疫/内分泌
细胞生物学
肿瘤
胰腺癌
CXCR2
CR2
肿瘤免疫
信号转导
发表日期：2025
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MyoD is essential in rhabdomyosarcoma by promoting survival through differentiation and CYLD

MyoD在横纹肌肉瘤中发挥着至关重要的作用，它通过促进分化和CYLD来提高细胞存活率。

期刊:iScience
影响因子:4.6
doi:10.1016/j.isci.2025.113149
Alexander R Oles ，Peter Y Yu ，Abasi-Ama Udeme ，Sudarshana Sharma ，Priya Londhe ，Benjamin R Pryce ，Erin E Talbert ，Eric M Hill ，Carlos J Miranda ，Brian K Kaspar ，Michael A Arnold ，Jack Hyland ，Cheryl A London ，Peter J Houghton ，David J Wang ，Ryan D Roberts ，Denis C Guttridge
细胞生物学
横纹肌肉瘤
CYLD
发表日期：2025
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