日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Polygenic Scores and Mood Disorder Onsets in the Context of Family History and Early Psychopathology

多基因评分与情绪障碍发病在家族史和早期精神病理学背景下的关系

Freeman, Kathryn; Zwicker, Alyson; Fullerton, Janice M; Hafeman, Danella M; van Haren, Neeltje E M; Merranko, John; Goldstein, Benjamin I; Stapp, Emma K; de la Serna, Elena; Moreno, Dolores; Sugranyes, Gisela; Mas, Sergi; Roberts, Gloria; Toma, Claudio; Schofield, Peter R; Edenberg, Howard J; Wilcox, Holly C; McInnis, Melvin G; Propper, Lukas; Pavlova, Barbara; Stewart, Samuel A; Denovan-Wright, Eileen M; Rouleau, Guy A; Castro-Fornieles, Josefina; Hillegers, Manon H J; Birmaher, Boris; Mitchell, Philip B; Alda, Martin; Nurnberger, John I; Uher, Rudolf

Enantiomeric Agonists of the Type 2 Cannabinoid Receptor Reduce Retinal Damage during Proliferative Vitreoretinopathy and Inhibit Hyperactive Microglia In Vitro.

2 型大麻素受体的对映体激动剂可减少增生性玻璃体视网膜病变期间的视网膜损伤,并在体外抑制过度活跃的小胶质细胞

Young Alexander P, Szczesniak Anna-Maria, Hsu Karolynn, Kelly Melanie E M, Denovan-Wright Eileen M

Synthetic cannabinoids reduce the inflammatory activity of microglia and subsequently improve neuronal survival in vitro

合成大麻素可降低小胶质细胞的炎症活动,从而提高体外神经元的存活率

Alexander P Young, Eileen M Denovan-Wright

Endothelin B receptor dysfunction mediates elevated myogenic tone in cerebral arteries from aged male Fischer 344 rats

内皮素B受体功能障碍介导老年雄性Fischer 344大鼠脑动脉肌源性张力升高

Young, Alexander P; Zhu, Jiequan; Bagher, Amina M; Denovan-Wright, Eileen M; Howlett, Susan E; Kelly, Melanie E M

Prevalence of methylenetetrahydrofolate reductase gene polymorphisms (C677T, and A1298C) among Saudi children receiving dental treatment

沙特阿拉伯接受牙科治疗的儿童中亚甲基四氢叶酸还原酶基因多态性(C677T 和 A1298C)的患病率

Bagher, Amina M; Young, Alexander P; Neamatallah, Thikryat; Al-Amoudi, Reham M; Bagher, Sara M; Denovan-Wright, Eileen M

Application of Fluorine- and Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of Cannabinoid 1 Receptor Positive Allosteric Modulators

氟和氮行走方法的应用:定义 2-苯基吲哚类大麻素 1 受体正变构调节剂的结构和功能多样性

Sumanta Garai, Pushkar M Kulkarni, Peter C Schaffer, Luciana M Leo, Asher L Brandt, Ayat Zagzoog, Tallan Black, Xiaoyan Lin, Dow P Hurst, David R Janero, Mary E Abood, Anaelle Zimmowitch, Alex Straiker, Roger G Pertwee, Melanie Kelly, Anna-Maria Szczesniak, Eileen M Denovan-Wright, Ken Mackie, Andre

Allosteric and orthosteric pharmacology of cannabidiol and cannabidiol-dimethylheptyl at the type 1 and type 2 cannabinoid receptors

大麻二酚及其二甲基庚基衍生物在1型和2型大麻素受体上的变构和正构药理学

Tham, Mylyne; Yilmaz, Orhan; Alaverdashvili, Mariam; Kelly, Melanie E M; Denovan-Wright, Eileen M; Laprairie, Robert B

Positive allosteric modulation of the type 1 cannabinoid receptor reduces the signs and symptoms of Huntington's disease in the R6/2 mouse model

1型大麻素受体的正向变构调节可减轻R6/2小鼠模型中亨廷顿病的体征和症状。

Laprairie, Robert B; Bagher, Amina M; Rourke, Jillian L; Zrein, Adel; Cairns, Elizabeth A; Kelly, Melanie E M; Sinal, Christopher J; Kulkarni, Pushkar M; Thakur, Ganesh A; Denovan-Wright, Eileen M

Huntington's disease pattern of transcriptional dysregulation in the absence of mutant huntingtin is produced by knockout of neuronal GLT-1

在没有突变亨廷顿蛋白的情况下,亨廷顿病的转录失调模式是由神经元 GLT-1 的敲除引起的

Robert B Laprairie, Geraldine T Petr, Yan Sun, Kathryn D Fischer, Eileen M Denovan-Wright, Paul A Rosenberg

Indomethacin Enhances Type 1 Cannabinoid Receptor Signaling

吲哚美辛增强 1 型大麻素受体信号传导

Robert B Laprairie, Kawthar A Mohamed, Ayat Zagzoog, Melanie E M Kelly, Lesley A Stevenson, Roger Pertwee, Eileen M Denovan-Wright, Ganesh A Thakur