日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Circulating Citrate Is Associated with Liver Fibrosis in Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis

循环柠檬酸盐与非酒精性脂肪肝和非酒精性脂肪性肝炎中的肝纤维化相关

Amjad, Waseem; Shalaurova, Irina; Garcia, Erwin; Gruppen, Eke G; Dullaart, Robin P F; DePaoli, Alex M; Jiang, Z Gordon; Lai, Michelle; Connelly, Margery A

The Commensal Microbe Veillonella as a Marker for Response to an FGF19 Analog in NASH

共生微生物韦荣氏球菌可作为非酒精性脂肪性肝炎患者对FGF19类似物反应的标志物

Loomba, Rohit; Ling, Lei; Dinh, Duy M; DePaoli, Alex M; Lieu, Hsiao D; Harrison, Stephen A; Sanyal, Arun J

Potent suppression of hydrophobic bile acids by aldafermin, an FGF19 analogue, across metabolic and cholestatic liver diseases

aldafermin(一种 FGF19 类似物)可有效抑制代谢性和胆汁淤积性肝病中的疏水性胆汁酸。

Sanyal, Arun J; Ling, Lei; Beuers, Ulrich; DePaoli, Alex M; Lieu, Hsiao D; Harrison, Stephen A; Hirschfield, Gideon M

NGM282 Improves Liver Fibrosis and Histology in 12 Weeks in Patients With Nonalcoholic Steatohepatitis

NGM282 可在 12 周内改善非酒精性脂肪性肝炎患者的肝纤维化和组织学

Harrison, Stephen A; Rossi, Stephen J; Paredes, Angelo H; Trotter, James F; Bashir, Mustafa R; Guy, Cynthia D; Banerjee, Rajarshi; Jaros, Mark J; Owers, Sandra; Baxter, Bryan A; Ling, Lei; DePaoli, Alex M

Dysregulation of serum bile acids and FGF19 in alcoholic hepatitis

酒精性肝炎中血清胆汁酸和FGF19的失调

Brandl, Katharina; Hartmann, Phillipp; Jih, Lily J; Pizzo, Donald P; Argemi, Josepmaria; Ventura-Cots, Meritxell; Coulter, Sally; Liddle, Christopher; Ling, Lei; Rossi, Stephen J; DePaoli, Alex M; Loomba, Rohit; Mehal, Wajahat Z; Fouts, Derrick E; Lucey, Michael R; Bosques-Padilla, Francisco; Mathurin, Philippe; Louvet, Alexander; Garcia-Tsao, Guadalupe; Verna, Elizabeth C; Abraldes, Juan G; Brown, Robert S Jr; Vargas, Victor; Altamirano, Jose; Caballería, Juan; Shawcross, Debbie; Stärkel, Peter; Ho, Samuel B; Bataller, Ramon; Schnabl, Bernd

Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice

调节肠道胆汁酸/法尼醇X受体/成纤维细胞生长因子15轴可改善小鼠酒精性肝病

Hartmann, Phillipp; Hochrath, Katrin; Horvath, Angela; Chen, Peng; Seebauer, Caroline T; Llorente, Cristina; Wang, Lirui; Alnouti, Yazen; Fouts, Derrick E; Stärkel, Peter; Loomba, Rohit; Coulter, Sally; Liddle, Christopher; Yu, Ruth T; Ling, Lei; Rossi, Stephen J; DePaoli, Alex M; Downes, Michael; Evans, Ronald M; Brenner, David A; Schnabl, Bernd

NGM282 for Treatment of Patients With Primary Biliary Cholangitis: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

NGM282治疗原发性胆汁性胆管炎患者的疗效:一项多中心、随机、双盲、安慰剂对照试验

Mayo, Marlyn J; Wigg, Alan J; Leggett, Barbara A; Arnold, Hays; Thompson, Alexander J; Weltman, Martin; Carey, Elizabeth J; Muir, Andrew J; Ling, Lei; Rossi, Stephen J; DePaoli, Alex M

Engineered FGF19 eliminates bile acid toxicity and lipotoxicity leading to resolution of steatohepatitis and fibrosis in mice

工程化FGF19可消除胆汁酸毒性和脂毒性,从而使小鼠的脂肪性肝炎和纤维化得到缓解。

Zhou, Mei; Learned, R Marc; Rossi, Stephen J; DePaoli, Alex M; Tian, Hui; Ling, Lei

Engineered fibroblast growth factor 19 reduces liver injury and resolves sclerosing cholangitis in Mdr2-deficient mice

工程化成纤维细胞生长因子19可减轻Mdr2缺陷小鼠的肝损伤并治愈硬化性胆管炎

Zhou, Mei; Learned, R Marc; Rossi, Stephen J; DePaoli, Alex M; Tian, Hui; Ling, Lei

Lymphoma in acquired generalized lipodystrophy

获得性全身性脂肪营养不良中的淋巴瘤

Brown, Rebecca J; Chan, Jean L; Jaffe, Elaine S; Cochran, Elaine; DePaoli, Alex M; Gautier, Jean-Francois; Goujard, Cecile; Vigouroux, Corinne; Gorden, Phillip