日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Targeting replication stress in neuroblastoma by exploiting the synergistic potential of second generation RRM2 and CHK1 inhibitors

利用第二代RRM2和CHK1抑制剂的协同作用，靶向治疗神经母细胞瘤中的复制应激

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-026-08514-6
Nelen, Iris H; Leys, Soetkin; Bekaert, Sarah-Lee; De Vloed, Fanny; Martens, Fien; Sanders, Ellen; Praveena Enton Raj, Angeline; Jeschke, Annika; Ohmura, Shunya; Grünewald, Thomas G P; Mus, Liselot M; Lammens, Tim; Van Roy, Nadine; De Wilde, Bram; Speleman, Frank; Van Hemelryk, Annelies; Depestel, Lisa; Durinck, Kaat
细胞生物学
CHK1
发表日期：2026
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Creative Arts Therapy for Anxiety, Depression, and Quality of Life in Cancer Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

创意艺术疗法对癌症患者焦虑、抑郁和生活质量的影响：随机对照试验的系统评价和荟萃分析

期刊:Psycho-Oncology
影响因子:3.5
doi:10.1002/pon.70425
Chou, Ashlyn S L; McKechnie, Tyler; Arora, Vikram; DePestel, Brianna; Wang, Austine; Parpia, Sameer; Calic, Goran; Staibano, Phillip; Derus, Alexandra; Guleria, Akanksha; Bhandari, Mohit; Thabane, Alex
肿瘤
肿瘤免疫
神经科学
发表日期：2026
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Second-Generation AURKA-Targeting PROTACs: Structural Optimization toward in Vivo Degradation in Neuroblastoma

第二代靶向AURKA的PROTAC：针对神经母细胞瘤体内降解的结构优化

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c01271
Krols, Simon; Rishfi, Muhammad; Martens, Fien; Van Hauwermeiren, Anouk; Sanders, Ellen; De Sutter, Pieter-Jan; Vermeulen, An; De Wever, Kaat; Bekaert, Sarah-Lee; Dolman, M Emmy M; Tax, Gabor; Kamili, Alvin; Fletcher, Jamie I; Depestel, Lisa; De Wilde, Bram; Durinck, Kaat; Van Calenbergh, Serge
细胞生物学
发表日期：2025
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Synergistic inhibition of CHK1 and MUS81 to combat replication stress resistance in high-risk neuroblastoma.

协同抑制 CHK1 和 MUS81 以对抗高危神经母细胞瘤的复制应激抵抗。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-29898-z
Hilgert Elien, Van Neste Christophe, Bekaert Sarah-Lee, Martens Fien, Vanhauwaert Suzanne, Sanders Ellen, Verstraelen Peter, Risseeuw Martijn, Westerhout Ellen M, Grannetia Mark A, Van Calenbergh Serge, Van Roy Nadine, De Vos Winnok H, Wolthuis Rob W F, Speleman Frank, Depestel Lisa, Durinck Kaat
细胞生物学
神经科学
CHK1
MUS81
发表日期：2025
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RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

RRM2 增强 MYCN 驱动的神经母细胞瘤形成，并与 CHK1 抑制一起充当协同靶点

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.abn1382
Carolina Nunes, Lisa Depestel, Liselot Mus, Kaylee M Keller, Louis Delhaye, Amber Louwagie, Muhammad Rishfi, Alex Whale, Neesha Kara, Simon R Andrews, Filemon Dela Cruz, Daoqi You, Armaan Siddiquee, Camila Takeno Cologna, Sam De Craemer, Emmy Dolman, Christoph Bartenhagen, Fanny De Vloed, Ellen Sand
神经
其它细胞
FCM
IF
IHC-P
WB
发表日期：2022
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PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation

PHF6 表达水平影响人类造血干细胞分化

期刊:Frontiers in Cell and Developmental Biology
影响因子:4.6
doi:10.3389/fcell.2020.599472
Siebe Loontiens, Anne-Catherine Dolens, Steven Strubbe, Inge Van de Walle, Finola E Moore, Lisa Depestel, Suzanne Vanhauwaert, Filip Matthijssens, David M Langenau, Frank Speleman, Pieter Van Vlierberghe, Kaat Durinck, Tom Taghon
发育与干细胞
干细胞
发表日期：2020
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Evaluation of Renal Safety Between Imipenem/Relebactam and Colistin Plus Imipenem in Patients With Imipenem-Nonsusceptible Bacterial Infections in the Randomized, Phase 3 RESTORE-IMI 1 Study

在随机、3期RESTORE-IMI 1研究中，评估亚胺培南/瑞巴坦与粘菌素联合亚胺培南治疗对亚胺培南不敏感的细菌感染患者的肾脏安全性

期刊:Open Forum Infectious Diseases
影响因子:3.8
doi:10.1093/ofid/ofaa054
Brown, Michelle L; Motsch, Johann; Kaye, Keith S; File, Thomas M; Boucher, Helen W; Vendetti, Neika; Aggrey, Angela; Joeng, Hee-Koung; Tipping, Robert W; Du, Jiejun; DePestel, Daryl D; Butterton, Joan R; Paschke, Amanda
炎症/感染
REST
微生物学
发表日期：2020
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A Combination Antibiogram Evaluation for Pseudomonas aeruginosa in Respiratory and Blood Sources from Intensive Care Unit (ICU) and Non-ICU Settings in U.S. Hospitals

美国医院重症监护室 (ICU) 和非 ICU 环境中呼吸道和血液来源的铜绿假单胞菌联合抗菌谱评价

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.02564-18
Puzniak, Laura; DePestel, Daryl D; Srinivasan, Arjun; Ye, Gang; Murray, John; Merchant, Sanjay; DeRyke, C Andrew; Gupta, Vikas
发表日期：2019
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Purification of high-quality RNA from a small number of fluorescence activated cell sorted zebrafish cells for RNA sequencing purposes

从少量经荧光激活细胞分选的斑马鱼细胞中纯化高质量RNA，用于RNA测序

期刊:BMC Genomics
影响因子:3.7
doi:10.1186/s12864-019-5608-2
Loontiens, Siebe; Depestel, Lisa; Vanhauwaert, Suzanne; Dewyn, Givani; Gistelinck, Charlotte; Verboom, Karen; Van Loocke, Wouter; Matthijssens, Filip; Willaert, Andy; Vandesompele, Jo; Speleman, Frank; Durinck, Kaat
细胞生物学
Cell sorting
cell sorting
IF
发表日期：2019
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Carbapenem-Nonsusceptible Gram-Negative Pathogens in ICU and Non-ICU Settings in US Hospitals in 2017: A Multicenter Study

2017年美国医院ICU和非ICU环境中碳青霉烯类耐药革兰氏阴性病原体：一项多中心研究

期刊:Open Forum Infectious Diseases
影响因子:3.8
doi:10.1093/ofid/ofy241
McCann, Eilish; Srinivasan, Arjun; DeRyke, C Andrew; Ye, Gang; DePestel, Daryl D; Murray, John; Gupta, Vikas
微生物学
发表日期：2018
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