日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The orientation of cholesterol's hydroxyl group affects its membrane dynamics and intracellular transport

胆固醇羟基的取向会影响其膜动力学和细胞内运输。

Lauritsen, Line; Pauli, Amanda Therese; Larsen, Miklas P W; Reinholdt, Peter; Scheidt, Holger A; Xu, Yuanjian; Covey, Douglas F; Depta, Laura; Bryce-Rogers, Hogan; Laraia, Luca; Kongsted, Jacob; Wüstner, Daniel

Identification of a Privileged Scaffold for Inhibition of Sterol Transport Proteins through the Synthesis and Ring Distortion of Diverse, Pseudo-Natural Products

通过合成和环扭曲多种拟天然产物,鉴定抑制甾醇转运蛋白的优势骨架

Bro, Frederik Simonsen; Depta, Laura; Dekker, Nienke J; Bryce-Rogers, Hogan P; Madsen, Maria Lillevang; Præstegaard, Kaia Fiil; Petersson, Tino; Whitmarsh-Everiss, Thomas; Kubus, Mariusz; Laraia, Luca

Identification of non-conventional small molecule degraders and stabilizers of squalene synthase

鉴定非常规小分子角鲨烯合酶降解剂和稳定剂

Hoock, Joseph G F; Rossetti, Cecilia; Bilgin, Mesut; Depta, Laura; Enemark-Rasmussen, Kasper; Christianson, John C; Laraia, Luca

Design and synthesis of Nrf2-derived hydrocarbon stapled peptides for the disruption of protein-DNA-interactions.

设计和合成 Nrf2 衍生的碳氢化合物交联肽,以破坏蛋白质-DNA 相互作用

Wiedemann Bianca, Kamps Dominic, Depta Laura, Weisner Jörn, Cvetreznik Jana, Tomassi Stefano, Gentz Sascha, Hoffmann Jan-Erik, Müller Matthias P, Koch Oliver, Dehmelt Leif, Rauh Daniel

Covalent-Allosteric Inhibitors to Achieve Akt Isoform-Selectivity

共价变构抑制剂实现Akt亚型选择性

Quambusch, Lena; Landel, Ina; Depta, Laura; Weisner, Jörn; Uhlenbrock, Niklas; Müller, Matthias P; Glanemann, Franziska; Althoff, Kristina; Siveke, Jens T; Rauh, Daniel