日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Defective DNA Damage Response is a Targetable Therapeutic Vulnerability in ESR1 Mutant Breast Cancer.

DNA损伤反应缺陷是ESR1突变型乳腺癌的一个可靶向治疗弱点。

Herzog Sarah K, Stevens Jessica H, Gu Guowei, Grimm Sandra L, Cardoza Kloma, Hawkins Autumn G M, Lin Hangqing, Ramos Daniela, Beyer Amanda R, Edwards David G, Dustin Derek, Yang Harry J, Liang Nicole, Khan Ashfia F, Bawa-Khalfe Tasneem, McGrail Daniel J, Lin Shiaw-Yih, Coarfa Cristian, Fuqua Suzanne A W

Three families of CD4-induced antibodies are associated with the capacity of plasma from people living with HIV to mediate ADCC in the presence of CD4-mimetics

三种 CD4 诱导抗体家族与 HIV 感染者血浆在 CD4 类似物存在下介导 ADCC 的能力有关

Alexandra Tauzin, Lorie Marchitto, Étienne Bélanger, Mehdi Benlarbi, Guillaume Beaudoin-Bussières, Jérémie Prévost, Derek Yang, Ta-Jung Chiu, Hung-Ching Chen, Catherine Bourassa, Halima Medjahed, Marek K Korzeniowski, Suneetha Gottumukkala, William D Tolbert, Jonathan Richard, Amos B Smith 3rd, Marz

NTB-A and 2B4 Natural Killer Cell Receptors Modulate the Capacity of a Cocktail of Non-Neutralizing Antibodies and a Small CD4-Mimetic to Eliminate HIV-1-Infected Cells by Antibody-Dependent Cellular Cytotoxicity

NTB-A 和 2B4 自然杀伤细胞受体调节非中和抗体混合物和小型 CD4 模拟物通过抗体依赖性细胞毒性消除 HIV-1 感染细胞的能力

Lorie Marchitto, Alexandra Tauzin, Mehdi Benlarbi, Guillaume Beaudoin-Bussières, Katrina Dionne, Étienne Bélanger, Debashree Chatterjee, Catherine Bourassa, Halima Medjahed, Derek Yang, Ta-Jung Chiu, Hung-Ching Chen, Amos B Smith Iii, Jonathan Richard, Andrés Finzi

Three families of CD4-induced antibodies are associated with the capacity of plasma from people living with HIV to mediate ADCC in presence of CD4-mimetics

三种 CD4 诱导抗体家族与 HIV 感染者血浆在 CD4 类似物存在下介导 ADCC 的能力有关

Alexandra Tauzin, Lorie Marchitto, Étienne Bélanger, Mehdi Benlarbi, Guillaume Beaudoin-Bussières, Jérémie Prévost, Derek Yang, Ta-Jung Chiu, Hung-Ching Chen, Catherine Bourassa, Halima Medjahed, Marek K Korzeniowski, Suneetha Gottumukkala, William D Tolbert, Jonathan Richard, Amos B Smith 3rd, Marz

Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity

二氢吲哚 CD4 模拟化合物介导强效和广泛的 HIV-1 抑制以及对抗体依赖性细胞毒性的敏化

Christopher J Fritschi, Saumya Anang, Zhen Gong, Mohammadjavad Mohammadi, Jonathan Richard, Catherine Bourassa, Kenny T Severino, Hannah Richter, Derek Yang, Hung-Ching Chen, Ta-Jung Chiu, Michael S Seaman, Navid Madani, Cameron Abrams, Andrés Finzi, Wayne A Hendrickson, Joseph G Sodroski, Amos B Sm

Pharmacophore Variants of the Macrocyclic Peptide Triazole Inactivator of HIV-1 Env

HIV-1 包膜蛋白大环肽三唑灭活剂的药效团变体

Monisha Gupta, Gabriela Canziani, Charles Ang, Mohammadjavad Mohammadi, Cameron F Abrams, Derek Yang, Amos B Smith 3rd, Irwin Chaiken

VE607 stabilizes SARS-CoV-2 Spike in the "RBD-up" conformation and inhibits viral entry

VE607 可稳定 SARS-CoV-2 刺突蛋白的“RBD 上调”构象,从而抑制病毒入侵。

Shilei Ding ,Irfan Ullah ,Shang Yu Gong ,Jonathan R Grover ,Mohammadjavad Mohammadi ,Yaozong Chen ,Dani Vézina ,Guillaume Beaudoin-Bussières ,Vijay Tailor Verma ,Guillaume Goyette ,Fleur Gaudette ,Jonathan Richard ,Derek Yang ,Amos B Smith 3rd ,Marzena Pazgier ,Marceline Côté ,Cameron Abrams ,Priti Kumar ,Walther Mothes ,Pradeep D Uchil ,Andrés Finzi ,Christian Baron

Development of Stem Cell-Derived Immune Cells for Off-the-Shelf Cancer Immunotherapies

开发用于现成癌症免疫疗法的干细胞衍生免疫细胞

Li, Yan-Ruide; Dunn, Zachary Spencer; Zhou, Yang; Lee, Derek; Yang, Lili

Interaction of the Hippo Pathway and Phosphatases in Tumorigenesis

Hippo通路与磷酸酶在肿瘤发生中的相互作用

Sarmasti Emami, Sahar; Zhang, Derek; Yang, Xiaolong

Orthodontic Treatment Need and the Psychosocial Impact of Malocclusion in 12-Year-Old Hong Kong Children

香港12岁儿童正畸治疗需求及错颌畸形的心理社会影响

Baram, Derek; Yang, Yanqi; Ren, Chong; Wang, Ziling; Wong, Ricky Wing Kit; Hägg, Urban; McGrath, Colman; Gu, Min