日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

AKAP79 Orchestrates a Cyclic AMP Signalosome Adjacent to Orai1 Ca2+ Channels

AKAP79 调控 Orai1 Ca2+ 通道附近的环磷酸腺苷信号体

Pulak Kar, Pradeep Barak, Anna Zerio, Yu-Ping Lin, Amy J Parekh, Val J Watts, Dermot M F Cooper, Manuela Zaccolo, Holger Kramer, Anant B Parekh

Structural and Functional Determinants of AC8 Trafficking, Targeting and Responsiveness in Lipid Raft Microdomains

脂筏微区中AC8转运、靶向和反应的结构和功能决定因素

Tabbasum, Valentina G; Cooper, Dermot M F

ADCY5 couples glucose to insulin secretion in human islets

ADCY5 将葡萄糖与人类胰岛中的胰岛素分泌联系起来

David J Hodson, Ryan K Mitchell, Lorella Marselli, Timothy J Pullen, Silvia Gimeno Brias, Francesca Semplici, Katy L Everett, Dermot M F Cooper, Marco Bugliani, Piero Marchetti, Vanessa Lavallard, Domenico Bosco, Lorenzo Piemonti, Paul R Johnson, Stephen J Hughes, Daliang Li, Wen-Hong Li, A M James

High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4)

高通量筛选鉴定出 Ceefourin 1 和 Ceefourin 2 为多药耐药蛋白 4 (MRP4) 的高选择性抑制剂

Leanna Cheung, Claudia L Flemming, Fujiko Watt, Nanako Masada, Denise M T Yu, Tony Huynh, Gwenaëlle Conseil, Amanda Tivnan, Alexander Polinsky, Andrei V Gudkov, Marcia A Munoz, Anasuya Vishvanath, Dermot M F Cooper, Michelle J Henderson, Susan P C Cole, Jamie I Fletcher, Michelle Haber, Murray D Nor

TRPC1 contributes to the Ca2+-dependent regulation of adenylate cyclases

TRPC1参与腺苷酸环化酶的Ca2+依赖性调节

Willoughby, Debbie; Ong, Hwei Ling; De Souza, Lorena Brito; Wachten, Sebastian; Ambudkar, Indu S; Cooper, Dermot M F

Unexpected Regulation of MicroRNA Activity by a Protein♦: The RNA-binding Protein TDP-43 Selectively Disrupts MicroRNA-1/206 Incorporation into the RNA-induced Silencing Complex

蛋白质对microRNA活性的意外调控♦:RNA结合蛋白TDP-43选择性地干扰microRNA-1/206整合到RNA诱导的沉默复合物中

Delint-Ramirez, Ilse; Willoughby, Debbie; Hammond, Gerald R V; Ayling, Laura J; Cooper, Dermot M F

Highly functionalized terpyridines as competitive inhibitors of AKAP-PKA interactions

高功能化三联吡啶作为AKAP-PKA相互作用的竞争性抑制剂

Schäfer, Gesa; Milić, Jelena; Eldahshan, Adeeb; Götz, Frank; Zühlke, Kerstin; Schillinger, Christian; Kreuchwig, Annika; Elkins, Jonathan M; Abdul Azeez, Kamal R; Oder, Andreas; Moutty, Marie C; Masada, Nanako; Beerbaum, Monika; Schlegel, Brigitte; Niquet, Sylvia; Schmieder, Peter; Krause, Gerd; von Kries, Jens Peter; Cooper, Dermot M F; Knapp, Stefan; Rademann, Jörg; Rosenthal, Walter; Klussmann, Enno

AKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complex

AKAP79、PKC、PKA 和 PDE4 参与 Gq 偶联的毒蕈碱受体和腺苷酸环化酶 2 cAMP 信号复合物。

Shen, Jia X; Cooper, Dermot M F

Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas Gβγ subunits exert opposing effects depending on the G-protein source.

毒蕈碱受体通过新的磷酸化位点刺激 AC2,而 Gββ 亚基则根据 G 蛋白的来源发挥相反的作用

Shen Jia X, Wachten Sebastian, Halls Michelle L, Everett Katy L, Cooper Dermot M F

A key phosphorylation site in AC8 mediates regulation of Ca(2+)-dependent cAMP dynamics by an AC8-AKAP79-PKA signalling complex

AC8 中的一个关键磷酸化位点通过 AC8-AKAP79-PKA 信号复合物介导 Ca(2+) 依赖性 cAMP 动态的调控。

Willoughby, Debbie; Halls, Michelle L; Everett, Katy L; Ciruela, Antonio; Skroblin, Philipp; Klussmann, Enno; Cooper, Dermot M F