日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Transforming growth factor beta (TGF-β) induces type 1 interferon signalling in systemic sclerosis keratinocytes through the chloride intracellular channel 4 (CLIC4).

转化生长因子β（TGF-β）通过氯离子细胞内通道4（CLIC4）诱导系统性硬化症角质形成细胞中的1型干扰素信号传导

期刊:Arthritis Research & Therapy
影响因子:4.6
doi:10.1186/s13075-025-03632-6
Wasson Christopher W, Dibb Sophie L, Caballero-Ruiz Begoña, Bamigbola Ifeoluwa E, Di Donato Stefano, Madourie-Clavane Eva M, Wells Rebecca, Kakkar Vishal, De Lorenzis Enrico, Bryon Jessica, Derrett-Smith Emma, Denton Christopher P, El-Sherbiny Yasser, Meakin Paul J, Ross Rebecca L, Del Galdo Francesco
信号转导
细胞生物学
发表日期：2025
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Clinical trajectories of hand function impairment in systemic sclerosis: an unmet clinical need across disease subsets

系统性硬化症手功能障碍的临床轨迹：不同疾病亚型中尚未满足的临床需求

期刊:RMD Open
影响因子:4.7
doi:10.1136/rmdopen-2023-003216
De Lorenzis, Enrico; Kakkar, Vishal; Di Donato, Stefano; Wilson, Michelle; Barnes, Theresa; Denton, Chris; Derrett-Smith, Emma; Douglas, Karen; Helliwell, Philip; Herrick, Ariane L; Saleem, Benazir; Nisar, Muhammad; Morley, Catherine; Green, Lorraine; Alcacer-Pitarch, Begonya; Del Galdo, Francesco
系统性硬化症
免疫/内分泌
发表日期：2024
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The 2024 British Society for Rheumatology guideline for management of systemic sclerosis-executive summary

2024年英国风湿病学会系统性硬化症管理指南执行摘要

期刊:Rheumatology
影响因子:4.4
doi:10.1093/rheumatology/keae390
Denton, Christopher P; De Lorenzis, Enrico; Roblin, Elen; Goldman, Nina; Alcacer-Pitarch, Begonya; Blamont, Emma; Buch, Maya H; Carulli, Maresa; Cotton, Caroline; Del Galdo, Francesco; Derrett-Smith, Emma; Douglas, Karen; Farrington, Sue; Fligelstone, Kim; Gompels, Luke; Griffiths, Bridget; Herrick, Ariane; Hughes, Michael; Pain, Clare; Pantano, Georgina; Pauling, John D; Prabu, Athiveeraramapandian; O'Donoghue, Nuala; Renzoni, Elisabetta A; Royle, Jeremy; Samaranayaka, Muditha; Spierings, Julia; Tynan, Aoife; Warburton, Louise; Ong, Voon H
系统性硬化症
免疫/内分泌
发表日期：2024
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The 2024 British Society for Rheumatology guideline for management of systemic sclerosis

2024年英国风湿病学会系统性硬化症管理指南

期刊:Rheumatology
影响因子:4.4
doi:10.1093/rheumatology/keae394
Denton, Christopher P; De Lorenzis, Enrico; Roblin, Elen; Goldman, Nina; Alcacer-Pitarch, Begonya; Blamont, Emma; Buch, Maya H; Carulli, Maresa; Cotton, Caroline; Del Galdo, Francesco; Derrett-Smith, Emma; Douglas, Karen; Farrington, Sue; Fligelstone, Kim; Gompels, Luke; Griffiths, Bridget; Herrick, Ariane; Hughes, Michael; Pain, Clare; Pantano, Georgina; Pauling, John D; Prabu, Athiveeraramapandian; O'Donoghue, Nuala; Renzoni, Elisabetta A; Royle, Jeremy; Samaranayaka, Muditha; Spierings, Julia; Tynan, Aoife; Warburton, Louise; Ong, Voon H
系统性硬化症
免疫/内分泌
发表日期：2024
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The value of ultrasound-defined tenosynovitis and synovitis in the prediction of persistent arthritis

超声定义的腱鞘炎和滑膜炎在预测持续性关节炎中的价值

期刊:Rheumatology
影响因子:4.4
doi:10.1093/rheumatology/keac199
Sahbudin, Ilfita; Singh, Ruchir; De Pablo, Paola; Rankin, Elizabeth; Rhodes, Benjamin; Justice, Elizabeth; Derrett-Smith, Emma; Amft, Nicole; Narayan, Nehal; McGrath, Catherine; Baskar, Sangeetha; Trickey, Jeanette; Maybury, Mark; Raza, Karim; Filer, Andrew
关节炎
滑膜炎
发表日期：2023
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Management of systemic sclerosis: British Society for Rheumatology guideline scope

系统性硬化症的管理：英国风湿病学会指南范围

期刊:Rheumatology Advances in Practice
影响因子:2.1
doi:10.1093/rap/rkad022
Denton, Christopher P; De Lorenzis, Enrico; Roblin, Elen; Goldman, Nina; Alcacer-Pitarch, Begonya; Blamont, Emma; Buch, Maya; Carulli, Maresa; Cotton, Caroline; Del Galdo, Francesco; Derrett-Smith, Emma; Douglas, Karen; Farrington, Sue; Fligelstone, Kim; Gompels, Luke; Griffiths, Bridget; Herrick, Ariane; Hughes, Michael; Pain, Clare; Pantano, Georgina; Pauling, John; Prabu, Athiveeraramapandian; O'Donoghue, Nuala; Renzoni, Elisabetta; Royle, Jeremy; Samaranayaka, Muditha; Spierings, Julia; Tynan, Aoife; Warburton, Louise; Ong, Voon
系统性硬化症
免疫/内分泌
发表日期：2023
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Integrated analysis of dermal blister fluid proteomics and genome-wide skin gene expression in systemic sclerosis: an observational study

系统性硬化症患者皮肤水疱液蛋白质组学与全基因组皮肤基因表达的综合分析：一项观察性研究

期刊:Lancet Rheumatology
影响因子:16.4
doi:10.1016/S2665-9913(22)00094-7
Clark, Kristina E N; Csomor, Eszter; Campochiaro, Corrado; Galwey, Nicholas; Nevin, Katherine; Morse, Mary A; Teo, Yee Voan; Freudenberg, Johannes; Ong, Voon H; Derrett-Smith, Emma; Wisniacki, Nicolas; Flint, Shaun M; Denton, Christopher P
系统性硬化症
免疫/内分泌
发表日期：2022
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Induction of Pro-Fibrotic CLIC4 in Dermal Fibroblasts by TGF-β/Wnt3a Is Mediated by GLI2 Upregulation

TGF-β/Wnt3a 诱导真皮成纤维细胞中促纤维化的 CLIC4 是由 GLI2 上调介导的

期刊:Cells
影响因子:5.1
doi:10.3390/cells11030530
Christopher W Wasson, Begoña Caballero-Ruiz, Justin Gillespie, Emma Derrett-Smith, Jamel Mankouri, Christopher P Denton, Gianluca Canettieri, Natalia A Riobo-Del Galdo, Francesco Del Galdo
信号转导
成纤维细胞
TGF-β
Wnt/β-Catenin
发表日期：2022
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The pan-PPAR agonist lanifibranor reduces development of lung fibrosis and attenuates cardiorespiratory manifestations in a transgenic mouse model of systemic sclerosis

泛PPAR激动剂lanifibranor可减少系统性硬化症转基因小鼠模型中的肺纤维化发展并减轻心肺症状。

期刊:Arthritis Research & Therapy
影响因子:4.6
doi:10.1186/s13075-021-02592-x
Derrett-Smith, Emma; Clark, Kristina E N; Shiwen, Xu; Abraham, David J; Hoyles, Rachel K; Lacombe, Olivier; Broqua, Pierre; Junien, Jean Louis; Konstantinova, Irena; Ong, Voon H; Denton, Christopher P
系统性硬化症
免疫/内分泌
发表日期：2021
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Scleroderma fibroblasts suppress angiogenesis via TGF-β/caveolin-1 dependent secretion of pigment epithelium-derived factor

硬皮病成纤维细胞通过TGF-β/caveolin-1依赖性分泌色素上皮衍生因子来抑制血管生成

期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/annrheumdis-2017-212120
Liakouli, Vasiliki; Elies, Jacobo; El-Sherbiny, Yasser Mohamed; Scarcia, Margherita; Grant, Gary; Abignano, Giuseppina; Derrett-Smith, Emma C; Esteves, Filomena; Cipriani, Paola; Emery, Paul; Denton, Christopher P; Giacomelli, Roberto; Mavria, Georgia; Del Galdo, Francesco
成纤维细胞
TGF-β
系统性硬化症
细胞生物学
血管生成
发表日期：2018
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