Imatinib reduces non-alcoholic fatty liver disease in obese mice by targeting inflammatory and lipogenic pathways in macrophages and liver
伊马替尼通过靶向巨噬细胞和肝脏中的炎症和脂肪生成通路,减轻肥胖小鼠的非酒精性脂肪肝疾病。
期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-018-32853-w
AlAsfoor, Shefaa; Rohm, Theresa V; Bosch, Angela J T; Dervos, Thomas; Calabrese, Diego; Matter, Matthias S; Weber, Achim; Cavelti-Weder, Claudia
巨噬细胞
炎症
炎症/感染
信号转导
巨噬细胞
代谢
肥胖
脂肪肝
细胞生物学
免疫/内分泌