日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Implementing the design cues of dissociation dynamics and transmetalation in gallium(iii) complexes to promote the anti-proliferative activity of ligands targeting intracellular iron(ii) trafficking

通过在镓(III)配合物中应用解离动力学和金属转移的设计线索,来增强靶向细胞内铁(II)转运的配体的抗增殖活性。

Dharmasivam, Mahendiran; Faiz, Sadia; Kaya, Busra; Wijesinghe, Tharushi P; Suleymanoglu, Mediha; Azad, Mahan Gholam; Richardson, Vera; Zahoor, Ameer Fawad; Kalinowski, Danuta; Lewis, William; Bernhardt, Paul V; Anjum, Rukhsana; Richardson, Des R

NDRG1 and its family members: More than just metastasis suppressor proteins and targets of thiosemicarbazones

NDRG1及其家族成员:不仅仅是转移抑制蛋白和硫代氨基脲的靶点

Azad, Mahan Gholam; Russell, Tiffany M; Gu, Xuanling; Zhao, Xiao; Richardson, Vera; Wijesinghe, Tharushi P; Babu, Golap; Guo, Xinnong; Kaya, Busra; Dharmasivam, Mahendiran; Deng, Zhao; Richardson, Des R

Differential transmetallation of complexes of the anti-cancer thiosemicarbazone, Dp4e4mT: effects on anti-proliferative efficacy, redox activity, oxy-myoglobin and oxy-hemoglobin oxidation

抗癌硫代氨基脲配合物Dp4e4mT的差异性金属转移:对抑制增殖功效、氧化还原活性、氧合肌红蛋白和氧合血红蛋白氧化的影响

Dharmasivam, Mahendiran; Kaya, Busra; Wijesinghe, Tharushi P; Richardson, Vera; Harmer, Jeffrey R; Gonzalvez, Miguel A; Lewis, William; Azad, Mahan Gholam; Bernhardt, Paul V; Richardson, Des R

Targeting lysosomes by design: novel N-acridine thiosemicarbazones that enable direct detection of intracellular drug localization and overcome P-glycoprotein (Pgp)-mediated resistance

通过设计靶向溶酶体:新型N-吖啶硫代氨基脲类化合物可直接检测细胞内药物定位并克服P-糖蛋白(Pgp)介导的耐药性

Kaya, Busra; Smith, Henry; Chen, Yanbing; Azad, Mahan Gholam; M Russell, Tiffany; Richardson, Vera; Bernhardt, Paul V; Dharmasivam, Mahendiran; Richardson, Des R

Multi-modal mechanisms of the metastasis suppressor, NDRG1: Inhibition of WNT/β-catenin signaling by stabilization of protein kinase Cα

转移抑制因子 NDRG1 的多模态机制:通过稳定蛋白激酶 Cα 抑制 WNT/β-catenin 信号传导

Mahan Gholam Azad, Mohammed Hussaini, Tiffany M Russell, Vera Richardson, Busra Kaya, Mahendiran Dharmasivam, Des R Richardson

The good Samaritan glutathione-S-transferase P1: An evolving relationship in nitric oxide metabolism mediated by the direct interactions between multiple effector molecules

谷胱甘肽-S-转移酶P1:一种由多种效应分子直接相互作用介导的一氧化氮代谢中不断演变的关系

Russell, Tiffany M; Richardson, Des R

Micromolding-based encapsulation of mesenchymal stromal cells in alginate for intraarticular injection in osteoarthritis

基于微成型的海藻酸盐间充质基质细胞包封用于骨关节炎关节内注射

Fabien Nativel, Audrey Smith, Jeremy Boulestreau, Charles Lépine, Julie Baron, Melanie Marquis, Caroline Vignes, Yoan Le Guennec, Joelle Veziers, Julie Lesoeur, François Loll, Boris Halgand, Denis Renard, Jerome Abadie, Benoit Legoff, Frederic Blanchard, Olivier Gauthier, Claire Vinatier, Anne des R

Ferritinophagy and α-Synuclein: Pharmacological Targeting of Autophagy to Restore Iron Regulation in Parkinson's Disease

铁蛋白自噬和α-突触核蛋白:通过药物靶向自噬来恢复帕金森病中的铁调节

Boag, Matthew K; Roberts, Angus; Uversky, Vladimir N; Ma, Linlin; Richardson, Des R; Pountney, Dean L

Glutathione-S-Transferases as Potential Targets for Modulation of Nitric Oxide-Mediated Vasodilation

谷胱甘肽-S-转移酶作为调节一氧化氮介导的血管舒张的潜在靶点

Russell, Tiffany M; Richardson, Des R

Targeting Wnt/tenascin C-mediated cross talk between pancreatic cancer cells and stellate cells via activation of the metastasis suppressor NDRG1

通过激活转移抑制因子 NDRG1 靶向 Wnt/tenascin C 介导的胰腺癌细胞和星状细胞之间的串扰

Bekesho Geleta, Faten S Tout, Syer Choon Lim, Sumit Sahni, Patric J Jansson, Minoti V Apte, Des R Richardson, Žaklina Kovačević