FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer
西妥昔单抗激活FOXO3a和MAPK p38，诱导细胞死亡并抑制细胞增殖，它们的表达可预测西妥昔单抗在结直肠癌中的疗效。
期刊:British Journal of Cancer
影响因子:6.8
doi:10.1038/bjc.2016.313
Marzi, L; Combes, E; Vié, N; Ayrolles-Torro, A; Tosi, D; Desigaud, D; Perez-Gracia, E; Larbouret, C; Montagut, C; Iglesias, M; Jarlier, M; Denis, V; Linares, L K; Lam, E W-F; Martineau, P; Del Rio, M; Gongora, C
FOXO3
肿瘤
肿瘤免疫
肠癌
细胞生物学
MAPK/ERK
