日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TNF receptor-associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation

TNF受体相关因子6与ALS相关的错误折叠超氧化物歧化酶1相互作用并促进其聚集

Sabrina Semmler,Myriam Gagné,Pranav Garg,Sarah R Pickles,Charlotte Baudouin,Emeline Hamon-Keromen,Laurie Destroismaisons,Yousra Khalfallah,Mathilde Chaineau,Elise Caron,Andrew N Bayne,Jean-François Trempe,Neil R Cashman,Alexandra T Star,Arsalan S Haqqani,Thomas M Durcan,Elizabeth M Meiering,Janice Robertson,Nathalie Grandvaux,Steven S Plotkin,Heidi M McBride,Christine Vande Velde

TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis

TDP-43 调节 hnRNP A1 的选择性剪接,从而产生肌萎缩侧索硬化症中易于聚集的变体

Jade-Emmanuelle Deshaies, Lulzim Shkreta, Alexander J Moszczynski, Hadjara Sidibé, Sabrina Semmler, Aurélien Fouillen, Estelle R Bennett, Uriya Bekenstein, Laurie Destroismaisons, Johanne Toutant, Quentin Delmotte, Kathryn Volkening, Stéphanie Stabile, Anaïs Aulas, Yousra Khalfallah, Hermona Soreq, 

Tau accumulation in the retina promotes early neuronal dysfunction and precedes brain pathology in a mouse model of Alzheimer's disease

在阿尔茨海默病小鼠模型中,Tau 在视网膜中的积累会促进早期神经元功能障碍,并先于大脑病理发生

Marius Chiasseu, Luis Alarcon-Martinez, Nicolas Belforte, Heberto Quintero, Florence Dotigny, Laurie Destroismaisons, Christine Vande Velde, Fany Panayi, Caroline Louis, Adriana Di Polo

ALS-linked misfolded SOD1 species have divergent impacts on mitochondria

与肌萎缩侧索硬化症 (ALS) 相关的错误折叠的 SOD1 物种对线粒体的影响各不相同

Pickles, Sarah; Semmler, Sabrina; Broom, Helen R; Destroismaisons, Laurie; Legroux, Laurine; Arbour, Nathalie; Meiering, Elizabeth; Cashman, Neil R; Vande Velde, Christine

Tau Accumulation, Altered Phosphorylation, and Missorting Promote Neurodegeneration in Glaucoma

Tau 积累、磷酸化改变和错分促进青光眼神经退行性病变

Marius Chiasseu, Jorge L Cueva Vargas, Laurie Destroismaisons, Christine Vande Velde, Nicole Leclerc, Adriana Di Polo

G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA

G3BP1 促进应激诱导的 RNA 颗粒相互作用以保存多聚腺苷酸化的 mRNA

Anaïs Aulas, Guillaume Caron, Christos G Gkogkas, Nguyen-Vi Mohamed, Laurie Destroismaisons, Nahum Sonenberg, Nicole Leclerc, J Alex Parker, Christine Vande Velde

Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1

通过免疫选择检测与 ALS 相关的错误折叠的 SOD1,揭示了线粒体损伤

Pickles, Sarah; Destroismaisons, Laurie; Peyrard, Sarah L; Cadot, Sarah; Rouleau, Guy A; Brown, Robert H Jr; Julien, Jean-Pierre; Arbour, Nathalie; Vande Velde, Christine

Endo-MitoEGFP mice: a novel transgenic mouse with fluorescently marked mitochondria in microvascular endothelial cells

Endo-MitoEGFP小鼠:一种新型转基因小鼠,其微血管内皮细胞中的线粒体带有荧光标记

Pickles, Sarah; Cadieux-Dion, Maxime; Alvarez, Jorge I; Lécuyer, Marc-Andre; Peyrard, Sarah L; Destroismaisons, Laurie; St-Onge, Lydia; Terouz, Simone; Cossette, Patrick; Prat, Alexandre; Vande Velde, Christine

Alzheimer’s disease candidate gene PION is differentially expressed in human prefrontal cortex

阿尔茨海默病候选基因PION在人类前额叶皮层中差异表达

Piton, A; Gauthier, J; Hamdan, F F; Lafrenière, R G; Yang, Y; Henrion, E; Laurent, S; Noreau, A; Thibodeau, P; Karemera, L; Spiegelman, D; Kuku, F; Duguay, J; Destroismaisons, L; Jolivet, P; Côté, M; Lachapelle, K; Diallo, O; Raymond, A; Marineau, C; Champagne, N; Xiong, L; Gaspar, C; Rivière, J-B; Tarabeux, J; Cossette, P; Krebs, M-O; Rapoport, J L; Addington, A; Delisi, L E; Mottron, L; Joober, R; Fombonne, E; Drapeau, P; Rouleau, G A; Wang, Jian; Saffen, David; Zhu, Min; Saffen, David