日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Identification of Novel Trypanosoma cruzi Proteasome Inhibitors Using a Luminescence-Based High-Throughput Screening Assay

使用基于发光的高通量筛选试验鉴定新型克氏锥虫蛋白酶体抑制剂

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.1
doi:10.1128/AAC.00309-19
Filip Zmuda, Lalitha Sastry, Sharon M Shepherd, Deuan Jones, Alison Scott, Peter D Craggs, Alvaro Cortes, David W Gray, Leah S Torrie, Manu De Rycker
发表日期：2019
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Genomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African Trypanosome

氧硼酸抗非洲锥虫作用方式的基因组学和蛋白质组学研究

期刊:PLoS Neglected Tropical Diseases
影响因子:
doi:10.1371/journal.pntd.0004299
Deuan C Jones, Bernardo J Foth, Michael D Urbaniak, Stephen Patterson, Han B Ong, Matthew Berriman, Alan H Fairlamb
信号转导
发表日期：2015
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Allosteric activation of trypanosomatid deoxyhypusine synthase by a catalytically dead paralog

催化失活的旁系同源物对锥虫脱氧羟脯氨酸合酶的变构激活

期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1074/jbc.M113.461137
Suong Nguyen, Deuan C Jones, Susan Wyllie, Alan H Fairlamb, Margaret A Phillips
发表日期：2013
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Synthesis and evaluation of indatraline-based inhibitors for trypanothione reductase

合成和评价基于印达曲林的锥虫硫还原酶抑制剂

期刊:ChemMedChem
影响因子:3.4
doi:10.1002/cmdc.201000442
Walton, Jeffrey G A; Jones, Deuan C; Kiuru, Paula; Durie, Alastair J; Westwood, Nicholas J; Fairlamb, Alan H
发表日期：2011
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Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis

鉴定出一种 κ-阿片类激动剂，作为治疗非洲人类锥虫病的强效选择性药物开发先导物

期刊:Biochemical Pharmacology
影响因子:5.3
doi:10.1016/j.bcp.2010.07.038
Deuan C Jones, Irene Hallyburton, Laste Stojanovski, Kevin D Read, Julie A Frearson, Alan H Fairlamb
信号转导
Human
发表日期：2010
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Development of a novel virtual screening cascade protocol to identify potential trypanothione reductase inhibitors

开发一种新型虚拟筛选级联方案，用于识别潜在的锥虫硫酮还原酶抑制剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm801306g
Perez-Pineiro, Rolando; Burgos, Asdrubal; Jones, Deuan C; Andrew, Lena C; Rodriguez, Hortensia; Suarez, Margarita; Fairlamb, Alan H; Wishart, David S
发表日期：2009
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Synthesis and evaluation of 1-(1-(Benzo[b]thiophen-2-yl)cyclohexyl)piperidine (BTCP) analogues as inhibitors of trypanothione reductase

合成并评价1-(1-(苯并[b]噻吩-2-基)环己基)哌啶(BTCP)类似物作为锥虫硫还原酶抑制剂

期刊:ChemMedChem
影响因子:3.4
doi:10.1002/cmdc.200900098
Patterson, Stephen; Jones, Deuan C; Shanks, Emma J; Frearson, Julie A; Gilbert, Ian H; Wyatt, Paul G; Fairlamb, Alan H
发表日期：2009
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Investigation of trypanothione reductase as a drug target in Trypanosoma brucei

对锥虫硫还原酶作为布氏锥虫药物靶点的研究

期刊:ChemMedChem
影响因子:3.4
doi:10.1002/cmdc.200900262
Spinks, Daniel; Shanks, Emma J; Cleghorn, Laura A T; McElroy, Stuart; Jones, Deuan; James, Daniel; Fairlamb, Alan H; Frearson, Julie A; Wyatt, Paul G; Gilbert, Ian H
发表日期：2009
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Improved tricyclic inhibitors of trypanothione reductase by screening and chemical synthesis

通过筛选和化学合成改进锥虫硫酮还原酶的三环类抑制剂

期刊:ChemMedChem
影响因子:3.4
doi:10.1002/cmdc.200900097
Richardson, John L; Nett, Isabelle R E; Jones, Deuan C; Abdille, Mohamed H; Gilbert, Ian H; Fairlamb, Alan H
发表日期：2009
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High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity

高通量筛选获得了具有抗锥虫活性的新型选择性锥虫硫酮还原酶抑制剂。

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2006.12.016
Martyn, Derek C; Jones, Deuan C; Fairlamb, Alan H; Clardy, Jon
发表日期：2007
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