日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Optimizing uPAR-targeting radiopeptides for improved tissue distribution: progress towards radionuclide therapy

优化靶向 uPAR 的放射性肽以改善组织分布：放射性核素治疗的进展

期刊:European Journal of Nuclear Medicine and Molecular Imaging
影响因子:7.6
doi:10.1007/s00259-025-07602-7
Vaccarin, Christian; Beyer, Darja; Schmid, Jerome V; Klein, Bastian; Jegathasan, Jathursa; Behera, Shreshtha; Deupi, Xavier; Schibli, Roger; Müller, Cristina
uPAR
uPA
发表日期：2026
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Cyclic peptide inhibitors function as molecular glues to stabilize Gq/11 heterotrimers

环肽抑制剂起到分子胶的作用，稳定Gq/11异源三聚体。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2418398122
Mühle, Jonas; Alenfelder, Judith; Rodrigues, Matthew J; Jürgenliemke, Lars; Guixà-González, Ramon; Grätz, Lukas; Andres, Fabio; Bacchin, Arianna; Hennig, Michael; Schihada, Hannes; Crüsemann, Max; König, Gabriele M; Schertler, Gebhard; Kostenis, Evi; Deupi, Xavier
发表日期：2025
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Coral anthozoan-specific opsins employ a novel chloride counterion for spectral tuning

珊瑚虫特有的视蛋白利用一种新型的氯离子反离子进行光谱调谐。

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.105451
Sakai, Yusuke; Sen, Saumik; Sugihara, Tomohiro; Kakeyama, Yukiya; Iwasaki, Makoto; Schertler, Gebhard F X; Deupi, Xavier; Koyanagi, Mitsumasa; Terakita, Akihisa
发表日期：2025
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Design and Preclinical Evaluation of Novel uPAR-Targeting Radiopeptides Modified with an Albumin-Binding Entity

利用白蛋白结合实体修饰的新型uPAR靶向放射性肽的设计和临床前评估

期刊:Molecular Pharmaceutics
影响因子:4.5
doi:10.1021/acs.molpharmaceut.5c00135
Beyer, Darja; Vaccarin, Christian; Schmid, Jerome V; Deberle, Luisa M; Deupi, Xavier; Schibli, Roger; Müller, Cristina
uPAR
uPA
发表日期：2025
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Active state structures of a bistable visual opsin bound to G proteins

与G蛋白结合的双稳态视蛋白的活性状态结构

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-53208-2
Tejero, Oliver; Pamula, Filip; Koyanagi, Mitsumasa; Nagata, Takashi; Afanasyev, Pavel; Das, Ishita; Deupi, Xavier; Sheves, Mordechai; Terakita, Akihisa; Schertler, Gebhard F X; Rodrigues, Matthew J; Tsai, Ching-Ju
信号转导
发表日期：2024
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Calcineurin-fusion facilitates cryo-EM structure determination of a Family A GPCR.

钙调磷酸酶融合促进了A家族GPCR的冷冻电镜结构测定

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2414544121
Xu Jun, Chen Geng, Wang Haoqing, Cao Sheng, Heng Jie, Deupi Xavier, Du Yang, Kobilka Brian K
其它
发表日期：2024
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Development of radiofluorinated MLN-4760 derivatives for PET imaging of the SARS-CoV-2 entry receptor ACE2

开发用于SARS-CoV-2进入受体ACE2 PET成像的放射性氟化MLN-4760衍生物

期刊:European Journal of Nuclear Medicine and Molecular Imaging
影响因子:7.6
doi:10.1007/s00259-024-06831-6
Wang, Jinling; Beyer, Darja; Vaccarin, Christian; He, Yingfang; Tanriver, Matthias; Benoit, Roger; Deupi, Xavier; Mu, Linjing; Bode, Jeffrey W; Schibli, Roger; Müller, Cristina
SARS-CoV-2
信号转导
ACE2
发表日期：2024
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A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides

SARS-CoV-2 进入受体的核成像工具：ACE2 选择性放射性肽的分子模型和临床前开发

期刊:Ejnmmi Research
影响因子:3.1
doi:10.1186/s13550-023-00979-2
Darja Beyer #, Christian Vaccarin #, Xavier Deupi, Ana Katrina Mapanao, Susan Cohrs, Fan Sozzi-Guo, Pascal V Grundler, Nicholas P van der Meulen, Jinling Wang, Matthias Tanriver, Jeffrey W Bode, Roger Schibli, Cristina Müller
代谢
免疫
心血管
新冠
FCM
IF
IHC-P
WB
ACE2
发表日期：2023
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β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR in living cells

β-arrestin1 和 2 在活细胞中与同一 GPCR 结合时表现出不同的磷酸化依赖性构象

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-022-33307-8
Raphael S Haider #, Edda S F Matthees #, Julia Drube, Mona Reichel, Ulrike Zabel, Asuka Inoue, Andy Chevigné, Cornelius Krasel, Xavier Deupi, Carsten Hoffmann
细胞生物学
表观遗传
其它细胞
发表日期：2022
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Structural Elements Directing G Proteins and β-Arrestin Interactions with the Human Melatonin Type 2 Receptor Revealed by Natural Variants

天然变异体揭示了指导 G 蛋白和 β-arrestin 与人类褪黑素 2 型受体相互作用的结构元件

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.1c00239
Plouffe, Bianca; Karamitri, Angeliki; Flock, Tilman; Gallion, Jonathan M; Houston, Shane; Daly, Carole A; Bonnefond, Amélie; Guillaume, Jean-Luc; Le Gouill, Christian; Froguel, Phillipe; Lichtarge, Olivier; Deupi, Xavier; Jockers, Ralf; Bouvier, Michel
Human
发表日期：2022
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