日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

β2-adrenergic Agonists Rescue Lysosome Acidification and Function in PSEN1 Deficiency by Reversing Defective ER-to-lysosome Delivery of ClC-7

β2-肾上腺素能激动剂通过逆转内质网到溶酶体的 ClC-7 传递缺陷来挽救 PSEN1 缺乏症中的溶酶体酸化和功能

Ju-Hyun Lee, Devin M Wolfe, Sandipkumar Darji, Mary Kate McBrayer, Daniel J Colacurcio, Asok Kumar, Philip Stavrides, Panaiyur S Mohan, Ralph A Nixon

Presenilin 1 Maintains Lysosomal Ca(2+) Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification

早老素1通过TRPML1调节vATPase介导的溶酶体酸化来维持溶酶体Ca(2+)稳态

Ju-Hyun Lee ,Mary Kate McBrayer ,Devin M Wolfe ,Luke J Haslett ,Asok Kumar ,Yutaka Sato ,Pearl P Y Lie ,Panaiyur Mohan ,Erin E Coffey ,Uday Kompella ,Claire H Mitchell ,Emyr Lloyd-Evans ,Ralph A Nixon

Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification

阿尔茨海默病中的自噬失败和溶酶体酸化缺陷的作用

Devin M Wolfe, Ju-Hyun Lee, Asok Kumar, Sooyeon Lee, Samantha J Orenstein, Ralph A Nixon

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations

溶酶体蛋白水解和自噬需要早老素 1,而阿尔茨海默病相关的 PS1 突变会破坏这些过程

Ju-Hyun Lee, W Haung Yu, Asok Kumar, Sooyeon Lee, Panaiyur S Mohan, Corrinne M Peterhoff, Devin M Wolfe, Marta Martinez-Vicente, Ashish C Massey, Guy Sovak, Yasuo Uchiyama, David Westaway, Ana Maria Cuervo, Ralph A Nixon