Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
蛋白质病理 tau 通过髓系细胞特异性 MyD88 和 NLRP3-ASC-炎症小体通路引发并激活白细胞介素-1β
期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2021.109720
Shanya Jiang, Nicole M Maphis, Jessica Binder, Devon Chisholm, Lea Weston, Walter Duran, Crina Peterson, Amber Zimmerman, Michael A Mandell, Stephen D Jett, Eileen Bigio, Changiz Geula, Nikolaos Mellios, Jason P Weick, Gary A Rosenberg, Eicke Latz, Michael T Heneka, Kiran Bhaskar
