Nonlinear response to cancer nanotherapy due to macrophage interactions revealed by mathematical modeling and evaluated in a murine model via CRISPR-modulated macrophage polarization
通过数学建模揭示巨噬细胞相互作用导致的癌症纳米疗法的非线性反应,并通过 CRISPR 调节的巨噬细胞极化在小鼠模型中进行评估
期刊:Cancer Immunology Immunotherapy
影响因子:8.1
doi:10.1007/s00262-020-02504-z
Fransisca Leonard, Louis T Curtis, Ahmed R Hamed, Carolyn Zhang, Eric Chau, Devon Sieving, Biana Godin, Hermann B Frieboes