日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Depleting IL1R2+ Tumor-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Anti-PD-1 Immunotherapy

利用易发生抗体依赖性细胞毒性(ADCC)的纳米抗体构建体清除肿瘤浸润的IL1R2+调节性T细胞,可提高抗PD-1免疫疗法的疗效。

Sana M Arnouk,Daliya Kancheva ,Helena Van Damme,Guillaume E Courtoy,Romina Mora Barthelmess,Jolien Van Craenenbroeck,Els Lebegge,Yvon Elkrim,Naela Assaf,Yves Heremans,Aleksandar Murgaski,Timo W M De Groof,Emile Clappaert ,Ayla Debraekeleer,Jan Brughmans,Gillian Blancke ,Máté Kiss ,Ramses Forsyth,Wim Waelput,Louis Boon,Nick Devoogdt,Catelijne Stortelers,Nadja van Boxel,Bruno Dombrecht,Lars Vereecke ,Cécile Vincke,Geert Raes,Damya Laoui,Jo A Van Ginderachter

Depleting IL1R2+ Tumor-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Anti-PD-1 Immunotherapy

利用易发生抗体依赖性细胞毒性(ADCC)的纳米抗体构建体清除肿瘤浸润的IL1R2+调节性T细胞,可提高抗PD-1免疫疗法的疗效。

Sana M Arnouk ,Daliya Kancheva ,Helena Van Damme ,Guillaume E Courtoy ,Romina Mora Barthelmess ,Jolien Van Craenenbroeck ,Els Lebegge ,Yvon Elkrim ,Naela Assaf ,Yves Heremans ,Aleksandar Murgaski ,Timo W M De Groof ,Emile Clappaert ,Ayla Debraekeleer ,Jan Brughmans ,Gillian Blancke ,Máté Kiss ,Ramses Forsyth ,Wim Waelput ,Louis Boon ,Nick Devoogdt ,Catelijne Stortelers ,Nadja van Boxel ,Bruno Dombrecht ,Lars Vereecke ,Cécile Vincke ,Geert Raes ,Damya Laoui ,Jo A Van Ginderachter

Optimizing antibody PET imaging: a comparative preclinical analysis of nanobody and minibody-like PET tracers

优化抗体PET成像:纳米抗体和迷你抗体样PET示踪剂的临床前比较分析

Katty Zeven ,Herlinde Dierick ,Matthijs Sevenois ,Henri Baudhuin ,Laurent Navarro ,Sonja Van den Block ,Jelena Saliën ,Karine Breckpot ,Jessica Bridoux ,Timo W M De Groof # ,Nick Devoogdt #

Preclinical development and selection of nanobody-based CAR-T cells targeting HER2-positive solid tumors

针对HER2阳性实体瘤的纳米抗体CAR-T细胞的临床前开发和筛选

Meeus, Fien; Van der Vreken, Arne; Autaers, Dorien; De Groof, Timo W M; Esprit, Arthur; Franceschini, Lorenzo; Parone, Philippe; Goyvaerts, Cleo; De Vlaeminck, Yannick; Devoogdt, Nick; Breckpot, Karine

Nanobody-based Pannexin1 channel inhibitors increase survival after cardiac ischemia/reperfusion

基于纳米抗体的Pannexin1通道抑制剂可提高心肌缺血/再灌注后的存活率。

Rusiecka, Olga M; Molica, Filippo; Clochard, Linda; Van Campenhout, Raf; De Groof, Timo W M; Bes, Viviane; Devoogdt, Nick; Muyldermans, Serge; Vinken, Mathieu; Kwak, Brenda R

A 2-year prospective study on the evolution of Low Anterior Resection Syndrome (LARS) following rectal cancer surgery

一项为期2年的前瞻性研究,旨在探讨直肠癌手术后低位前切除综合征(LARS)的演变情况。

Lauwereins, L; D'Hoore, A; Coeckelberghs, E; Fieuws, S; Wolthuis, A; Bislenghi, G; Van Molhem, Y; Van Geluwe, B; Debrun, L; Devoogdt, N; De Groef, A; Asnong, A; Geraerts, I

LymphSens study: the enigma of subjective lymphoedema - how often and why do patients report lymphoedema after breast cancer treatment without an objective measurable swelling? The role of lymphatic and sensory processing problems: a protocol for a multicentre prospective longitudinal study

LymphSens 研究:主观性淋巴水肿之谜——乳腺癌治疗后,患者为何经常报告淋巴水肿,却无客观可测量的肿胀?淋巴和感觉处理问题的作用:一项多中心前瞻性纵向研究方案

Gursen, Ceren; Meeus, Mira; Verbeelen, Kaat; Vets, Nieke; Spincemaille, Laura; Smeets, Ann; Thomis, Sarah; Fieuws, Steffen; Vanderheyden, Hans; Gebruers, Nick; Tjalma, Wiebren; Johansson, Karin; Keeley, Vaughan; De Groef, An; Devoogdt, Nele

Study protocol for a pragmatic randomised controlled trial in Belgian primary care and hospital settings on the effectiveness of an eHealth self-management support programme consisting of pain education and coaching of activity needs in breast cancer survivors with persistent pain: the PECAN trial

一项在比利时基层医疗机构和医院开展的实用性随机对照试验的研究方案,旨在评估一项包含疼痛教育和活动需求指导的电子健康自我管理支持计划对持续性疼痛乳腺癌幸存者的有效性:PECAN试验

De Groef, An; Dams, Lore; Moseley, G Lorimer; Heathcote, Lauren C; Wiles, Louise K; Catley, Mark; Vogelzang, Anna; Hibbert, Peter; Morlion, Bart; Van Overbeke, Marthe; Tack, Emma; Van Dijck, Sophie; Devoogdt, Nele; Gursen, Ceren; De Paepe, Annick L; Mertens, Michel; van Olmen, Josefien; Willem, Lander; Tjalma, Wiebren; Nevelsteen, Ines; Neven, Patrick; Vanhoudt, Rani; Wildemeersch, Davina; De Backere, Femke; Fieuws, Steffen; Crombez, Geert; Meeus, Mira

Post-operative incidence of lymphedema after RARP with or without extended pelvic lymph node dissection in a cohort study

队列研究:根治性前列腺切除术(RARP)伴或不伴扩大盆腔淋巴结清扫术后淋巴水肿的发生率

Clinckaert, Andries; Ysenbaardt, Laura; Bijnens, Annabel; Van Calster, Charlotte; Geraerts, Inge; Joniau, Steven; Devoogdt, Nele; Bijnens, Luc; Everaerts, Wouter

Compression terms: Defining terminology of compression therapy - An international compression club consensus document

压缩疗法术语:压缩疗法术语定义——国际压缩疗法俱乐部共识文件

Mosti, Giovanni; Benigni, Jean P; Bohbot, Serge; Devoogdt, Nele; Forner-Cordero, Isabel; da Matta, Eduardo; Rastel, Didier; Roes, Claas; Thomis, Sara