日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cytoskeletal control in adult microglia is essential to restore neurodevelopmental synaptic and cognitive deficits.

成年小胶质细胞的细胞骨架控制对于恢复神经发育突触和认知缺陷至关重要

Kessels Sofie, Trippaers Chloë, Mertens Melanie, Hamad Ibrahim, Rombaut Ben, Janssen Art, Ramanathan Keerthana, Duwé Sam, Gharghani Adelaïde M, Theuwis Rune, Delbroek Amber, Vangansewinkel Tim, Berden Lisa, Beeken Jolien, Vandormael Patrick, Poovathingal Suresh, Voets Thomas, Kleinewietfeld Markus, Nguyen Laurent, Antel Jack P, Healy Luke M, Cowley Sally A, Ishizuka Koko, Rigo Jean-Michel, Hendrix Jelle, Vanmierlo Tim, Dewachter Ilse, Alpizar Yeranddy A, Sawa Akira, Brône Bert

A peek into the pipeline: Expert views on emerging therapies

一窥研发管线:专家对新兴疗法的看法

Dewachter, Ilse; Höglinger, Günter U; Drucker, Daniel J; Brown, Christine E; Martin, Roland; Chang, Anne Bernadette; Chotirmall, Sanjay Haresh; Qi, Xiaolong; Shaw, Pamela

The Impact of Exercise Training on the Brain and Cognition in Type 2 Diabetes, and its Physiological Mediators: A Systematic Review

运动训练对2型糖尿病患者大脑和认知功能的影响及其生理调节机制:系统评价

Vandersmissen, Jitske; Dewachter, Ilse; Cuypers, Koen; Hansen, Dominique

Gastrointestinal Dysfunction and Low-Grade Inflammation Associate With Enteric Neuronal Amyloid-β in a Model for Amyloid Pathology.

胃肠功能障碍和低度炎症与肠神经元淀粉样蛋白β相关,是淀粉样蛋白病理学模型的一部分

Tasnády Kinga Réka, Jehoul Reindert, de Ravé Manuel Gutiérrez, Gijbels Marion J, Brône Bert, Dewachter Ilse, Melotte Veerle, Boesmans Werend

Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models

塑造阿尔茨海默病疾病修饰药物临床前开发的未来:tau蛋白传播模型的系统性综述

Basheer, Neha; Buee, Luc; Brion, Jean-Pierre; Smolek, Tomas; Muhammadi, Muhammad Khalid; Hritz, Jozef; Hromadka, Tomas; Dewachter, Ilse; Wegmann, Susanne; Landrieu, Isabelle; Novak, Petr; Mudher, Amritpal; Zilka, Norbert

Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study

淀粉样蛋白和Tau蛋白与阿尔茨海默病临床前期认知功能的关系:一项纵向研究

Hanseeuw, Bernard J; Betensky, Rebecca A; Jacobs, Heidi I L; Schultz, Aaron P; Sepulcre, Jorge; Becker, J Alex; Cosio, Danielle M Orozco; Farrell, Michelle; Quiroz, Yakeel T; Mormino, Elizabeth C; Buckley, Rachel F; Papp, Kathryn V; Amariglio, Rebecca A; Dewachter, Ilse; Ivanoiu, Adrian; Huijbers, Willem; Hedden, Trey; Marshall, Gad A; Chhatwal, Jasmeer P; Rentz, Dorene M; Sperling, Reisa A; Johnson, Keith

Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo

基于Tau蛋白相互作用组图谱的鉴定表明,Otub1是Tau蛋白去泛素化酶,参与体外和体内病理性Tau蛋白的积累。

Wang, Peng; Joberty, Gerard; Buist, Arjan; Vanoosthuyse, Alexandre; Stancu, Ilie-Cosmin; Vasconcelos, Bruno; Pierrot, Nathalie; Faelth-Savitski, Maria; Kienlen-Campard, Pascal; Octave, Jean-Noël; Bantscheff, Marcus; Drewes, Gerard; Moechars, Diederik; Dewachter, Ilse

What is the evidence that tau pathology spreads through prion-like propagation?

有什么证据表明tau蛋白病变是通过类似朊病毒的传播方式扩散的?

Mudher, Amrit; Colin, Morvane; Dujardin, Simon; Medina, Miguel; Dewachter, Ilse; Alavi Naini, Seyedeh Maryam; Mandelkow, Eva-Maria; Mandelkow, Eckhard; Buée, Luc; Goedert, Michel; Brion, Jean-Pierre

Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing

利用高灵敏度分裂荧光素酶检测法分析参与APP二聚化的区域及其对加工过程的影响

Decock, Marie; El Haylani, Laetitia; Stanga, Serena; Dewachter, Ilse; Octave, Jean-Noël; Smith, Steven O; Constantinescu, Stefan N; Kienlen-Campard, Pascal

Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice

向tau转基因小鼠脑内注射预先形成的合成tau蛋白纤维可引发广泛的tau蛋白病变和神经元丢失。

Peeraer, Eve; Bottelbergs, Astrid; Van Kolen, Kristof; Stancu, Ilie-Cosmin; Vasconcelos, Bruno; Mahieu, Michel; Duytschaever, Hilde; Ver Donck, Luc; Torremans, An; Sluydts, Ellen; Van Acker, Nathalie; Kemp, John A; Mercken, Marc; Brunden, Kurt R; Trojanowski, John Q; Dewachter, Ilse; Lee, Virginia M Y; Moechars, Diederik