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日期影响因子

Mechanism of 30S subunit recognition and modification by the conserved bacterial ribosomal RNA methyltransferase RsmI

保守的细菌核糖体RNA甲基转移酶RsmI识别和修饰30S亚基的机制

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2523453123

Barmada, Mohamed I; McGinity, Erin N; Nandi, Suparno; Dey, Debayan; Zelinskaya, Natalia; Harris, George M; Comstock, Lindsay R; Dunham, Christine M; Conn, Graeme L

发表日期：2026

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Design, Synthesis, and Evaluation of Novel Inhibitors of Aminoglycoside-Resistance 16S Ribosomal RNA Methyltransferases

新型氨基糖苷类抗性16S核糖体RNA甲基转移酶抑制剂的设计、合成与评价

期刊:ChemMedChem

影响因子:3.4

doi:10.1002/cmdc.202500889

Deprez, Benjamin E; Dey, Debayan; Zelinskaya, Natalia; Csatary, Erika E; Yang, Qimin Winnie; Nie, Minhua; Conn, Graeme L; Wuest, William M

发表日期：2026

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Dominant-negative PSMB10 disrupts immunoproteasome assembly and leads to transient T lymphopenia.

显性负性 PSMB10 会破坏免疫蛋白酶体的组装，导致短暂性 T 淋巴细胞减少症。

doi:10.70962/jhi.20250129

Ghosh Sujal, Wang Yuqin, Schultheiss Christoph, Borkhardt Arndt, Dafun Angelique Sanchez, Knipp Liisa, Marwitz Sebastian, Ehl Stephan, Soulard Clara, Haddad Elie, Dey Debayan, Evans Grace, Golwala Zainab M, Bennstein Sabrina B, Laws Hans-JÃ¼rgen, Rohlfs Meino, Magg Thomas, Binder Mascha, Kreins Alexandra Y, Bousquet Marie-Pierre, Marcoux Julien, Klein Christoph, Conn Graeme L, Meiners Silke, Hauck Fabian

细胞生物学

发表日期：2026

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Basis for selective drug evasion of an aminoglycoside-resistance ribosomal RNA modification.

选择性逃避氨基糖苷类抗性核糖体RNA修饰的基础

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-63278-5

Dey Debayan, Mattingly Jacob M, Zelinskaya Natalia, Dunham Christine M, Conn Graeme L

发表日期：2025

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Distant ribose 2'-O-methylation of 23S rRNA helix 69 pre-orders the capreomycin drug binding pocket at the ribosome subunit interface

23S rRNA 69号螺旋的远端核糖2'-O-甲基化预先调控了核糖体亚基界面处的卷曲霉素药物结合口袋。

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkaf618

Nandi, Suparno; Dey, Debayan; Srinivas, Pooja; Dunham, Christine M; Conn, Graeme L

发表日期：2025

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Discovery of First-in-Class Inhibitors Targeting a Pathogen-Associated Aminoglycoside-Resistance 16S rRNA Methyltransferase

发现靶向病原体相关氨基糖苷类耐药性16S rRNA甲基转移酶的首创抑制剂

期刊:ACS Infectious Diseases

影响因子:3.8

doi:10.1021/acsinfecdis.5c00297

Dey, Debayan; Deprez, Benjamin E; Zelinskaya, Natalia; Castro, Jose M; Wuest, William M; Conn, Graeme L

发表日期：2025

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Molecular basis of tRNA substrate recognition and modification by the atypical SPOUT methyltransferase Trm10

非典型SPOUT甲基转移酶Trm10识别和修饰tRNA底物的分子基础

doi:10.64898/2025.12.12.694034

Nandi, Suparno; Strassler, Sarah E; Dey, Debayan; Krishnamohan, Aiswarya; Harris, George M; Comstock, Lindsay R; Jackman, Jane E; Conn, Graeme L

发表日期：2025

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Mechanism of 30S subunit recognition and modification by the conserved bacterial ribosomal RNA methyltransferase RsmI

保守的细菌核糖体RNA甲基转移酶RsmI识别和修饰30S亚基的机制

doi:10.1101/2025.08.28.672957

Barmada, Mohamed I; McGinity, Erin N; Nandi, Suparno; Dey, Debayan; Zelinskaya, Natalia; Harris, George M; Comstock, Lindsay R; Dunham, Christine M; Conn, Graeme L

发表日期：2025

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Structural and functional diversity of Resistance-Nodulation-Division (RND) efflux pump transporters with implications for antimicrobial resistance

耐药性-结节-分裂（RND）外排泵转运蛋白的结构和功能多样性及其对抗菌素耐药性的影响

期刊:Microbiology and Molecular Biology Reviews

影响因子:7.8

doi:10.1128/mmbr.00089-23

Kavanaugh, Logan G; Dey, Debayan; Shafer, William M; Conn, Graeme L

发表日期：2024

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DISTANT RIBOSE 2'-O-METHYLATION OF 23S rRNA HELIX 69 PRE-ORDERS THE CAPREOMYCIN DRUG BINDING POCKET AT THE RIBOSOME SUBUNIT INTERFACE

23S rRNA螺旋69的远端核糖2'-O-甲基化预先排列了核糖体亚基界面处的卷曲霉素药物结合口袋。

doi:10.1101/2024.11.05.619916

Nandi, Suparno; Dey, Debayan; Srinivas, Pooja; Dunham, Christine M; Conn, Graeme L

发表日期：2024

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