Cell-autonomous IL6ST activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment.
细胞自主的IL6ST激活通过STAT3/ARF/p53驱动的衰老抑制前列腺癌的发展，并赋予肿瘤免疫活性微环境
期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-024-02114-8
Sternberg Christina, Raigel Martin, Limberger Tanja, Trachtová KarolÃna, Schlederer Michaela, Lindner Desiree, Kodajova Petra, Yang Jiaye, Ziegler Roman, Kalla Jessica, Stoiber Stefan, Dey Saptaswa, Zwolanek Daniela, Neubauer Heidi A, Oberhuber Monika, Redmer Torben, Hejret Václav, Tichy Boris, Tomberger Martina, Harbusch Nora S, Pencik Jan, Tangermann Simone, Bystry Vojtech, Persson Jenny L, Egger Gerda, Pospisilova Sarka, Eferl Robert, Wolf Peter, Sternberg Felix, Högler Sandra, Lagger Sabine, Rose-John Stefan, Kenner Lukas
细胞生物学
肿瘤
前列腺癌
Senescence
P53
肿瘤免疫
