日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Verekitug, a Novel Antibody Antagonist to the TSLP Receptor in Adults with Asthma: A 32-Week Randomized Phase 1b Multiple Ascending-Dose Trial

Verekitug,一种新型的TSLP受体抗体拮抗剂,用于治疗成人哮喘:一项为期32周的随机1b期多剂量递增试验

Singh, Dave; Brickman, Chaim M; Lloyd, Peter; Kalra, Ashish; Biswas, Subhabrata; Sinha, Arkadeep; Mulvanny, Alex; Sivapalasingam, Sumathi; Becker, Oren M; Deykin, Aaron

Sex Differences in Dietary-Induced Liver Steatosis and Insulin Receptor-Related Signaling in Aged Mice Lacking Serotonin Transporter

缺乏血清素转运蛋白的老年小鼠中饮食诱导的肝脂肪变性和胰岛素受体相关信号传导的性别差异

Cespuglio, Raymond; Zabegalov, Konstantin; de Munter, Johannes P M; Gorlova, Anna; Chaprov, Kirill; Rogacheva, Daria; Askarova, Sholpan; Schmitt-Böhrer, Angelika; Deykin, Aleksei; Lesch, Klaus-Peter; Strekalova, Tatyana

Partial Serotonin Transporter Deficiency Modulates Plasma Metabolome, Arginine-Nitric Oxide Pathway and Emotional Behavior in Mice Exposed to Western Diet

部分血清素转运蛋白缺乏会调节暴露于西方饮食的小鼠的血浆代谢组、精氨酸-一氧化氮通路和情绪行为。

Gorlova, Anna; Cespuglio, Raymond; Schmitt-Böhrer, Angelika; Deykin, Alexey; Kalueff, Allan V; Lebedeva, Ksenia; Nedorubov, Andrey; Shulte, Gabriela Ortega; Svirin, Evgeniy; Lyundup, Aleksey; Lesch, Klaus-Peter; Strekalova, Tatyana

Potent painkiller from spider venom antagonizes P2X3 receptors without dysgeusia.

蜘蛛毒液中的强效止痛剂可拮抗 P2X3 受体,且不会引起味觉障碍

Oparin Peter, Khokhlova Oksana, Cherkashin Aleksandr, Nadezhdin Kirill, Palikov Victor, Palikova Yulia, Korolkova Yuliya, Mosharova Irina, Rogachevskaja Olga, Baranov Mikhail, Shaidullova Ksenia, Ermakova Elizaveta, Lushpa Vladislav, Bruter Alexandra, Deykin Alexey, Ivanova Elena, Silaeva Yulia, Dyachenko Igor, Bocharov Eduard, Sitdikova Guzel, Andreev-Andrievskiy Alexander, Poteryaev Dmitry, Shuster Alexander, Murashev Arkady, Kolesnikov Stanislav, Stepanenko Vasiliy, Grishin Eugene, Vassilevski Alexander

Positioning of sperm tail longitudinal columns depends on NSUN7, an RNA-binding protein destabilizing elongated spermatid transcripts.

精子尾部纵柱的定位取决于 NSUN7,这是一种 RNA 结合蛋白,可破坏细长精子细胞转录本的稳定性

Guseva Ekaterina A, Averina Olga A, Isaev Sergey V, Pletnev Philipp I, Bragina Elizaveta E, Permyakov Oleg A, Buev Vitaly S, Priymak Anastasia V, Emelianova Mariia A, Pshanichnaya Lizaveta, Romanov Evgeny A, Novikova Svetlana E, Petriukov Kirill S, Golovina Anna Ya, Grigorieva Olga O, Manskikh Vasily N, Korshunova Diana S, Silaeva Yuliya Yu, Deykin Alexey V, Rubtsova Maria P, Zgoda Victor G, Mazur Alexander M, Prokhortchouk Egor B, Dontsova Olga A, Sergiev Petr V

Prenatal ethanol exposure results in cell-type, age, and sex-dependent differences in the neonatal striatum that coincide with early motor deficits.

产前接触乙醇会导致新生儿纹状体出现细胞类型、年龄和性别相关的差异,这些差异与早期运动缺陷相吻合

Tousley Adelaide R, Deykin Ilana, Koc Betul, Yeh Pamela Wl, Yeh Hermes H

p2rx3 Knockout Mice Have Altered Energy Metabolism in Hippocampal Neurons

p2rx3基因敲除小鼠海马神经元能量代谢发生改变

Zelentsova, A S; Pokrovskii, M V; Patrakhanov, E A; Shmigerova, V S; Skorkina, M Yu; Deykin, A V

Bioinformatic analysis of the regulatory potential of tagging SNPs provides evidence of the involvement of genes encoding the heat-resistant obscure (Hero) proteins in the pathogenesis of cardiovascular diseases

对标记SNP调控潜力的生物信息学分析表明,编码耐热隐匿(Hero)蛋白的基因参与了心血管疾病的发病机制。

Shilenok, Vladislav V; Shilenok, Irina V; Soldatov, Vladislav O; Orlov, Yuriy L; Kobzeva, Ksenia A; Deykin, Alexey V; Bushueva, Olga Yu

Gene Therapy Approach for Treatment of Obese Agouti Mice

基因疗法治疗肥胖的刺鼠

Yunin, Maxim A; Boychenko, Stanislav S; Lebedev, Petr; Deykin, Alexey V; Pokrovskii, Mikhail V; Egorov, Alexander D

C11orf58 (Hero20) Gene Polymorphism: Contribution to Ischemic Stroke Risk and Interactions with Other Heat-Resistant Obscure Chaperones

C11orf58 (Hero20) 基因多态性:对缺血性中风风险的影响及其与其他耐热隐匿分子伴侣的相互作用

Shilenok, Irina; Kobzeva, Ksenia; Soldatov, Vladislav; Deykin, Alexey; Bushueva, Olga