日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Quantitative Profiling of Nanoscopic Protein Aggregates Reveals Specific Fingerprint of TDP-43-Positive Assemblies in Motor Neuron Disease.

纳米级蛋白质聚集体的定量分析揭示了运动神经元疾病中 TDP-43 阳性聚集体的特定指纹。

Cox Dezerae, Burke Melanie, Milani Sara, White Matthew A, Waldron Fergal M, Böken Dorothea, Lobanova Evgeniia, Sreedharan Jemeen, Gregory Jenna M, Klenerman David

Single-molecule observations of human small heat shock proteins in complex with aggregation-prone client proteins.

利用单分子方法观察人类小热休克蛋白与易聚集底物蛋白的复合物

Rice Lauren, Marzano Nicholas, Cox Dezerae, Skewes Bailey, van Oijen Antoine M, Ecroyd Heath

Single-Molecule Characterization and Super-Resolution Imaging of Alzheimer's Disease-Relevant Tau Aggregates in Human Samples

人类样本中与阿尔茨海默病相关的tau蛋白聚集体的单分子表征和超分辨率成像

Böken, Dorothea; Cox, Dezerae; Burke, Melanie; Lam, Jeff Y L; Katsinelos, Taxiarchis; Danial, John S H; Fertan, Emre; McEwan, William A; Rowe, James B; Klenerman, David

PERCEPT: Replacing binary p-value thresholding with scaling for more nuanced identification of sample differences

PERCEPT:用尺度变换代替二元p值阈值法,以更细致地识别样本差异

Cox, Dezerae; Hatters, Danny M

Hidden information on protein function in censuses of proteome foldedness

蛋白质组折叠普查中隐藏的蛋白质功能信息

Dezerae Cox, Ching-Seng Ang, Nadinath B Nillegoda, Gavin E Reid, Danny M Hatters

Sequence grammar underlying the unfolding and phase separation of globular proteins

球状蛋白质展开和相分离背后的序列语法

Kiersten M Ruff, Yoon Hee Choi, Dezerae Cox, Angelique R Ormsby, Yoochan Myung, David B Ascher, Sheena E Radford, Rohit V Pappu, Danny M Hatters

Deletion of the Plasmodium falciparum exported protein PTP7 leads to Maurer's clefts vesiculation, host cell remodeling defects, and loss of surface presentation of EMP1

恶性疟原虫输出蛋白 PTP7 的缺失导致 Maurer 裂隙囊泡形成、宿主细胞重塑缺陷以及 EMP1 表面呈递丧失

Olivia M S Carmo, Gerald J Shami, Dezerae Cox, Boyin Liu, Adam J Blanch, Snigdha Tiash, Leann Tilley, Matthew W A Dixon

A biosensor of protein foldedness identifies increased "holdase" activity of chaperones in the nucleus following increased cytosolic protein aggregation

蛋白质折叠的生物传感器可识别细胞质蛋白质聚集增加后细胞核内分子伴侣的“holdase”活性增加

Candice B Raeburn, Angelique R Ormsby, Dezerae Cox, Chloe A Gerak, Christian Makhoul, Nagaraj S Moily, Simon Ebbinghaus, Alex Dickson, Gawain McColl, Danny M Hatters

Protein painting reveals pervasive remodeling of conserved proteostasis machinery in response to pharmacological stimuli

蛋白质绘画揭示了在药物刺激下保守的蛋白质稳态机制的普遍重塑

Dezerae Cox, Angelique R Ormsby, Gavin E Reid, Danny M Hatters

PINK1 signalling in neurodegenerative disease

PINK1信号通路在神经退行性疾病中的作用

Whiten, Daniel R; Cox, Dezerae; Sue, Carolyn M