日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Recombination Is Responsible for the Increased Recovery of Drug-Resistant Mutants with Hypermutated Genomes in Resting Yeast Diploids Expressing APOBEC Deaminases

在表达APOBEC脱氨酶的静止酵母二倍体中,重组是导致具有高突变基因组的耐药突变体回收率增加的原因。

Lada, Artem G; Stepchenkova, Elena I; Zhuk, Anna S; Kliver, Sergei F; Rogozin, Igor B; Polev, Dmitrii E; Dhar, Alok; Pavlov, Youri I

Disruption of Transcriptional Coactivator Sub1 Leads to Genome-Wide Re-distribution of Clustered Mutations Induced by APOBEC in Active Yeast Genes

转录共激活因子Sub1的破坏导致APOBEC诱导的活性酵母基因中簇状突变的全基因组重新分布

Lada, Artem G; Kliver, Sergei F; Dhar, Alok; Polev, Dmitrii E; Masharsky, Alexey E; Rogozin, Igor B; Pavlov, Youri I

Genome-wide mutation avalanches induced in diploid yeast cells by a base analog or an APOBEC deaminase

碱基类似物或APOBEC脱氨酶在二倍体酵母细胞中诱导全基因组突变雪崩

Lada, Artem G; Stepchenkova, Elena I; Waisertreiger, Irina S R; Noskov, Vladimir N; Dhar, Alok; Eudy, James D; Boissy, Robert J; Hirano, Masayuki; Rogozin, Igor B; Pavlov, Youri I

AID/APOBEC cytosine deaminase induces genome-wide kataegis

AID/APOBEC胞嘧啶脱氨酶诱导全基因组kataegis

Lada, Artem G; Dhar, Alok; Boissy, Robert J; Hirano, Masayuki; Rubel, Aleksandr A; Rogozin, Igor B; Pavlov, Youri I

Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis mice.

G93A-SOD1 肌萎缩侧索硬化症小鼠的适应性免疫神经保护

Banerjee Rebecca, Mosley R Lee, Reynolds Ashley D, Dhar Alok, Jackson-Lewis Vernice, Gordon Paul H, Przedborski Serge, Gendelman Howard E

Novel role of TGF-beta in differential astrocyte-TIMP-1 regulation: implications for HIV-1-dementia and neuroinflammation

TGF-β在星形胶质细胞-TIMP-1差异性调控中的新作用:对HIV-1痴呆和神经炎症的启示

Dhar, Alok; Gardner, Jessica; Borgmann, Kathleen; Wu, Li; Ghorpade, Anuja