日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Long-Term Use of Proton Pump Inhibitors Disrupts Intestinal Tight Junction Barrier and Exaggerates Experimental Colitis

长期使用质子泵抑制剂会破坏肠道紧密连接屏障并加剧实验性结肠炎

Meghali Nighot, Pei-Luan Liao, Nathan Morris, Dennis McCarthy, Viszwapriya Dharmaprakash, Inam Ullah Khan, Shannon Dalessio, Kushal Saha, Ashwinkumar Subramaniam Ganapathy, Alexandra Wang, Wei Ding, Gregory Yochum, Walter Koltun, Prashant Nighot, Thomas Ma

Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathways

α-生育酚醌通过AhR和Nrf2通路差异性地调节claudin蛋白,从而增强肠上皮紧密连接屏障。

Ashwinkumar Subramenium Ganapathy ,Kushal Saha ,Alexandra Wang ,Priya Arumugam ,Viszwapriya Dharmaprakash ,Gregory Yochum ,Walter Koltun ,Meghali Nighot ,Gary Perdew ,Todd A Thompson ,Thomas Ma ,Prashant Nighot

Bifidobacterium bifidum Enhances the Intestinal Epithelial Tight Junction Barrier and Protects against Intestinal Inflammation by Targeting the Toll-like Receptor-2 Pathway in an NF-κB-Independent Manner

双歧杆菌以 NF-κB 非依赖性方式靶向 Toll 样受体 2 通路,增强肠道上皮紧密连接屏障,防止肠道炎症

Rana Al-Sadi, Viszwapriya Dharmaprakash, Prashant Nighot, Shuhong Guo, Meghali Nighot, Toan Do, Thomas Y Ma

IL1B Increases Intestinal Tight Junction Permeability by Up-regulation of MIR200C-3p, Which Degrades Occludin mRNA

IL1B通过上调MIR200C-3p增加肠道紧密连接的通透性,而MIR200C-3p会降解Occludin mRNA。

Rawat, Manmeet; Nighot, Meghali; Al-Sadi, Rana; Gupta, Yash; Viszwapriya, Dharmaprakash; Yochum, Gregory; Koltun, Walter; Ma, Thomas Y

The Gut Microbiome and Alcoholic Liver Disease: Ethanol Consumption Drives Consistent and Reproducible Alteration in Gut Microbiota in Mice

肠道微生物组和酒精性肝病:乙醇摄入导致小鼠肠道微生物群发生持续且可重复的改变

Erick S LeBrun, Meghali Nighot, Viszwapriya Dharmaprakash, Anand Kumar, Chien-Chi Lo, Patrick S G Chain, Thomas Y Ma

covR Mediated Antibiofilm Activity of 3-Furancarboxaldehyde Increases the Virulence of Group A Streptococcus

covR介导的3-呋喃甲醛抗生物膜活性增强A群链球菌的毒力

Ashwinkumar Subramenium, Ganapathy; Viszwapriya, Dharmaprakash; Iyer, Prasanth Mani; Balamurugan, Krishnaswamy; Karutha Pandian, Shunmugiah

Ultradeep 16S rRNA sequencing analysis of geographically similar but diverse unexplored marine samples reveal varied bacterial community composition

对地理位置相似但种类繁多的未探索海洋样本进行超深16S rRNA测序分析,揭示了不同的细菌群落组成。

Aravindraja, Chairmandurai; Viszwapriya, Dharmaprakash; Karutha Pandian, Shunmugiah

(E)-3-(4-Chloro-phen-yl)-1-(2,4-dichloro-5-fluoro-phen-yl)prop-2-en-1-one

(E)-3-(4-氯苯基)-1-(2,4-二氯-5-氟苯基)丙-2-烯-1-酮

Fun, Hoong-Kun; Chantrapromma, Suchada; Patil, P S; Karthikeyan, M S; Dharmaprakash, S M

S-Benzyl-thio-uronium 3-nitro-benzene-sulfonate

S-苄基硫脲3-硝基苯磺酸盐

Fun, Hoong-Kun; Jebas, Samuel Robinson; Razak, Ibrahim Abdul; Deepak D'Silva, E; Patil, P S; Dharmaprakash, S M

(E)-1-(2-Thien-yl)-3-(2,4,5-trimethoxy-phen-yl)prop-2-en-1-one

(E)-1-(2-噻吩基)-3-(2,4,5-三甲氧基苯基)丙-2-烯-1-酮

Fun, Hoong-Kun; Jebas, Samuel Robinson; Patil, P S; Dharmaprakash, S M