日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

M6 metabolite contributes to the efficacy of the Rac/Cdc42 inhibitor MBQ-167 in metastatic breast cancer.

M6 代谢物有助于 Rac/Cdc42 抑制剂 MBQ-167 在转移性乳腺癌中的疗效。

期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-25-1319
Grafals-Ruiz Nilmary, Medina Julia I, Colon Gonzalez Jessica, Torres-Sanchez Anamaris, Martin-Ortiz Karla M, Vlaar Cornelis P, Duconge Jorge, Rodriguez-Orengo Jose, Dharmawardhane Suranganie
乳腺癌
代谢
CDC42
发表日期：2026
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Novel Inhibition of Central Carbon Metabolism Pathways by Rac and CDC42 inhibitor MBQ167 and Paclitaxel.

Rac 和 CDC42 抑制剂 MBQ167 和紫杉醇对中心碳代谢途径的新型抑制作用

期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-23-0803
Cruz-Collazo Ailed M, Katsara Olga, Grafals-Ruiz Nilmary, Colon Gonzalez Jessica, Dorta-Estremera Stephanie, Carlo Victor P, Chorna Nataliya, Schneider Robert J, Dharmawardhane Suranganie
代谢
发表日期：2024
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Synthesis of Novel Heterocyclic Ferrocenyl Chalcones and Their Biological Evaluation

新型杂环二茂铁基查尔酮的合成及其生物活性评价

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.3c01830
Alsina-Sánchez, Ámbar M; Montalvo-Vázquez, Sebastián; Grafals-Ruiz, Nilmary; Acosta, Carmen; Ormé, Emily M; Rodríguez, Israel; Delgado-Rivera, Sara M; Tinoco, Arthur D; Dharmawardhane, Suranganie; Montes-González, Ingrid C
发表日期：2023
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Rac inhibition as a novel therapeutic strategy for EGFR/HER2 targeted therapy resistant breast cancer

RAC抑制剂作为EGFR/HER2靶向治疗耐药乳腺癌的一种新型治疗策略

期刊:BMC Cancer
影响因子:3.4
doi:10.1186/s12885-021-08366-7
Borrero-García, Luis D; Del Mar Maldonado, Maria; Medina-Velázquez, Julia; Troche-Torres, Angel L; Velazquez, Luis; Grafals-Ruiz, Nilmary; Dharmawardhane, Suranganie
肿瘤
HER2
肿瘤免疫
EGF
治疗耐药
乳腺癌
EGFR
发表日期：2021
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Physiologically-Based Pharmacokinetic/Pharmacodynamic Model of MBQ-167 to Predict Tumor Growth Inhibition in Mice

基于生理的MBQ-167药代动力学/药效学模型预测小鼠肿瘤生长抑制

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics12100975
Reig-López, Javier; Maldonado, María Del Mar; Merino-Sanjuan, Matilde; Cruz-Collazo, Ailed M; Ruiz-Calderón, Jean F; Mangas-Sanjuán, Victor; Dharmawardhane, Suranganie; Duconge, Jorge
肿瘤
肿瘤免疫
发表日期：2020
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Simalikalactone D, a Potential Anticancer Compound from Simarouba tulae, an Endemic Plant of Puerto Rico

Simalikalactone D，一种来自波多黎各特有植物Simarouba tulae的潜在抗癌化合物

期刊:Plants-Basel
影响因子:4.1
doi:10.3390/plants9010093
Mendez, Belmari; Reyes, Jeyshka; Conde, Isabel; Ramos, Zulma; Lozada, Eunice; Cruz, Ailed M; Asencio, Gabriela; Carvajal, Augusto; Dharmawardhane, Suranganie; Piñero-Cruz, Dalice M; Hernández, Eliud; Vivas, Pablo; Ospina, Claudia A
肿瘤
肿瘤免疫
发表日期：2020
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Pharmacokinetics of the Rac/Cdc42 Inhibitor MBQ-167 in Mice by Supercritical Fluid Chromatography-Tandem Mass Spectrometry

采用超临界流体色谱-串联质谱法研究小鼠体内Rac/Cdc42抑制剂MBQ-167的药代动力学

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.9b01641
Maldonado, María Del Mar; Rosado-González, Gabriela; Bloom, Joseph; Duconge, Jorge; Ruiz-Calderón, Jean F; Hernández-O'Farrill, Eliud; Vlaar, Cornelis; Rodríguez-Orengo, José F; Dharmawardhane, Suranganie
发表日期：2019
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Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer

转移性癌症中双重Rac/Cdc42抑制剂MBQ-167的特性分析

期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-16-0442
Humphries-Bickley, Tessa; Castillo-Pichardo, Linette; Hernandez-O'Farrill, Eliud; Borrero-Garcia, Luis D; Forestier-Roman, Ingrid; Gerena, Yamil; Blanco, Manuel; Rivera-Robles, Michael J; Rodriguez-Medina, José R; Cubano, Luis A; Vlaar, Cornelis P; Dharmawardhane, Suranganie
肿瘤
肿瘤免疫
发表日期：2017
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Anti-Breast Cancer Potential of Quercetin via the Akt/AMPK/Mammalian Target of Rapamycin (mTOR) Signaling Cascade

槲皮素通过Akt/AMPK/mTOR信号通路发挥抗乳腺癌作用

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0157251
Rivera Rivera, Amilcar; Castillo-Pichardo, Linette; Gerena, Yamil; Dharmawardhane, Suranganie
肿瘤
mTOR
肿瘤免疫
信号转导
乳腺癌
AMPK
发表日期：2016
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Dietary grape polyphenol resveratrol increases mammary tumor growth and metastasis in immunocompromised mice

膳食中的葡萄多酚白藜芦醇会促进免疫缺陷小鼠乳腺肿瘤的生长和转移。

期刊:BMC Complementary and Alternative Medicine
影响因子:3.4
doi:10.1186/1472-6882-13-6
Castillo-Pichardo, Linette; Cubano, Luis A; Dharmawardhane, Suranganie
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2013
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