Dhruma相关文献与解析，生知库 | 链接生命科学的每一步

Heath Bryony, Kaira Bubacarr G, Thakker Dhruma, Mohammed Omar J, Choudhury Ruhul, Dave Foram, Vaghela Poonam, Dubinina Elena, Parsons Tina, Durrant Lindy, Vankemmelbeke Mireille

细胞生物学

肺癌

发表日期：2025

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Interleukin-1 receptor-associated kinase 4 (IRAK4) is a critical regulator of inflammatory signalling through toll-like receptors 4 and 7/8 in murine and human lungs

白细胞介素-1受体相关激酶4（IRAK4）是小鼠和人类肺部通过Toll样受体4和7/8进行炎症信号传导的关键调节因子。

期刊:British Journal of Pharmacology

影响因子:7.7

doi:10.1111/bph.16509

Sayers, Ian; Thakker, Dhruma; Billington, Charlotte; Kreideweiss, Stefan; Grundl, Marc A; Bouyssou, Thierry; Thamm, Sven; Kreuz, Sebastian; Hall, Ian P

SC134-TCB Targeting Fucosyl-GM1, a T Cell-Engaging Antibody with Potent Antitumor Activity in Preclinical Small Cell Lung Cancer Models

SC134-TCB 靶向岩藻糖基-GM1，这是一种在临床前小细胞肺癌模型中具有强效抗肿瘤活性的 T 细胞结合抗体

期刊:Molecular Cancer Therapeutics

影响因子:5.3

doi:10.1158/1535-7163.MCT-24-0187

Foram Dave #, Poonam Vaghela #, Bryony Heath, Zuzana Dunster, Elena Dubinina, Dhruma Thakker, Katie Mann, Joe Chadwick, Gaëlle Cane, Bubacarr G Kaira, Omar J Mohammed, Ruhul Choudhury, Samantha Paston, Tina Parsons, Mireille Vankemmelbeke, Lindy Durrant

Transcriptomics using lung resection material to advance our understanding of COPD and idiopathic pulmonary fibrosis pathogenesis

利用肺切除组织进行转录组学分析，以增进我们对慢性阻塞性肺疾病和特发性肺纤维化发病机制的理解。

期刊:Erj Open Research

影响因子:4

doi:10.1183/23120541.00061-2024

Rakkar, Kamini; Thakker, Dhruma; Portelli, Michael A; Hall, Ian; Schlüter, Holger; Sayers, Ian

Proinflammatory Effects in Ex Vivo Human Lung Tissue of Respirable Smoke Extracts from Indoor Cooking in Nepal

尼泊尔室内烹饪产生的可吸入烟雾提取物对离体人肺组织的促炎作用

期刊:Annals of the American Thoracic Society

影响因子:5.4

doi:10.1513/AnnalsATS.201911-827OC

Kc, Binaya; Mahapatra, Parth Sarathi; Thakker, Dhruma; Henry, Amanda P; Billington, Charlotte K; Sayers, Ian; Puppala, Siva Praveen; Hall, Ian P

Human

发表日期：2020

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Defining a role for lung function associated gene GSTCD in cell homeostasis

确定肺功能相关基因 GSTCD 在细胞稳态中的作用

期刊:Respiratory Research

影响因子:6.6

doi:10.1186/s12931-019-1146-3

Amanda P Henry, Kelly Probert, Ceri E Stewart, Dhruma Thakker, Sangita Bhaker, Sheyda Azimi, Ian P Hall, Ian Sayers

SC134-deruxtecan, a fucosyl-GM1 targeting ADC for small cell lung cancer therapy.

SC134-deruxtecan，一种靶向岩藻糖基-GM1的抗体药物偶联物，用于治疗小细胞肺癌

Interleukin-1 receptor-associated kinase 4 (IRAK4) is a critical regulator of inflammatory signalling through toll-like receptors 4 and 7/8 in murine and human lungs

白细胞介素-1受体相关激酶4（IRAK4）是小鼠和人类肺部通过Toll样受体4和7/8进行炎症信号传导的关键调节因子。

SC134-TCB Targeting Fucosyl-GM1, a T Cell-Engaging Antibody with Potent Antitumor Activity in Preclinical Small Cell Lung Cancer Models

SC134-TCB 靶向岩藻糖基-GM1，这是一种在临床前小细胞肺癌模型中具有强效抗肿瘤活性的 T 细胞结合抗体

Transcriptomics using lung resection material to advance our understanding of COPD and idiopathic pulmonary fibrosis pathogenesis

利用肺切除组织进行转录组学分析，以增进我们对慢性阻塞性肺疾病和特发性肺纤维化发病机制的理解。

Proinflammatory Effects in Ex Vivo Human Lung Tissue of Respirable Smoke Extracts from Indoor Cooking in Nepal

尼泊尔室内烹饪产生的可吸入烟雾提取物对离体人肺组织的促炎作用

Defining a role for lung function associated gene GSTCD in cell homeostasis

确定肺功能相关基因 GSTCD 在细胞稳态中的作用