日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Quantifying Risk of Delayed QT Prolongation of Ipatasertib in Preclinical and Clinical Studies in Cancer Patients

量化伊帕他替尼在癌症患者临床前和临床研究中引起QT间期延长的风险

期刊:Cts-Clinical and Translational Science
影响因子:2.8
doi:10.1111/cts.70298
Poon, Victor; Sutaria, Dhruvitkumar; Prell, Rodney; Halpern, Wendy; Wong, Lisa; Harris, Adam; Wilkins, Justin; Yoshida, Kenta; Sane, Rucha
肿瘤
肿瘤免疫
发表日期：2025
文献求助 收藏

Population pharmacokinetics and humanized dosage regimens matching the peak, area, trough, and range of amikacin plasma concentrations in immune-competent murine bloodstream and lung infection models

在免疫功能正常的鼠血流和肺部感染模型中，研究了阿米卡星血浆浓度的峰浓度、峰面积、谷浓度和浓度范围，并制定了相应的群体药代动力学和人源化给药方案。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.01394-23
Jiao, Yuanyuan; Yan, Jun; Sutaria, Dhruvitkumar S; Lu, Peggy; Vicchiarelli, Michael; Reyna, Zeferino; Ruiz-Delgado, Juan; Burk, Elizabeth; Moon, Eugene; Shah, Nirav R; Spellberg, Brad; Bonomo, Robert A; Drusano, George L; Louie, Arnold; Luna, Brian M; Bulitta, Jürgen B
炎症/感染
免疫/内分泌
发表日期：2024
文献求助 收藏

Individual Components of Polymyxin B Modeled via Population Pharmacokinetics to Design Humanized Dosage Regimens for a Bloodstream and Lung Infection Model in Immune-Competent Mice

通过群体药代动力学模型构建多粘菌素B各组分模型，以设计适用于免疫功能正常小鼠血液和肺部感染模型的人源化给药方案

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00197-23
Jiao, Yuanyuan; Yan, Jun; Vicchiarelli, Michael; Sutaria, Dhruvitkumar S; Lu, Peggy; Reyna, Zeferino; Spellberg, Brad; Bonomo, Robert A; Drusano, George L; Louie, Arnold; Luna, Brian M; Bulitta, Jürgen B
炎症/感染
Human
免疫/内分泌
发表日期：2023
文献求助 收藏

Risk Factors of Hyperglycemia After Treatment With the AKT Inhibitor Ipatasertib in the Prostate Cancer Setting: A Machine Learning-Based Investigation

前列腺癌患者接受AKT抑制剂伊帕他替治疗后发生高血糖的危险因素：一项基于机器学习的研究

期刊:JCO Clinical Cancer Informatics
影响因子:2.8
doi:10.1200/CCI.22.00168
Harun, Rashed; Sane, Rucha; Yoshida, Kenta; Sutaria, Dhruvitkumar S; Jin, Jin Y; Lu, James
AKT
肿瘤
前列腺癌
肿瘤免疫
发表日期：2023
文献求助 收藏

Drug-Drug Interaction Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Ipatasertib in Combination with Darolutamide in Patients with Advanced Prostate Cancer

药物相互作用研究：评估伊帕他替尼联合达罗鲁胺治疗晚期前列腺癌患者的药代动力学、安全性和耐受性

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics14102101
Sutaria, Dhruvitkumar S; Rasuo, Grozdana; Harris, Adam; Johnson, Ryan; Miles, Dale; Gallo, Jorge Daniel; Sane, Rucha
肿瘤
前列腺癌
肿瘤免疫
发表日期：2022
文献求助 收藏

Characterization of exposure-response relationships of ipatasertib in patients with metastatic castration-resistant prostate cancer in the IPATential150 study

IPATential150 研究中转移性去势抵抗性前列腺癌患者接受 ipatasertib 治疗的暴露-反应关系特征分析

期刊:Cancer Chemotherapy and Pharmacology
影响因子:2.3
doi:10.1007/s00280-022-04488-2
Kotani, Naoki; Wilkins, Justin J; Wade, Janet R; Dang, Steve; Sutaria, Dhruvitkumar S; Yoshida, Kenta; Sundrani, Sameer; Ding, Hao; Garcia, Josep; Hinton, Heather; Sane, Rucha; Chanu, Pascal
肿瘤
前列腺癌
肿瘤免疫
发表日期：2022
文献求助 收藏

Combating Multidrug-Resistant Bacteria by Integrating a Novel Target Site Penetration and Receptor Binding Assay Platform Into Translational Modeling

将新型靶位点渗透和受体结合分析平台整合到转化模型中以对抗多重耐药菌

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.2205
Lang, Yinzhi; Shah, Nirav R; Tao, Xun; Reeve, Stephanie M; Zhou, Jieqiang; Moya, Bartolome; Sayed, Alaa R M; Dharuman, Suresh; Oyer, Jeremiah L; Copik, Alicja J; Fleischer, Brett A; Shin, Eunjeong; Werkman, Carolin; Basso, Kari B; Deveson Lucas, Deanna; Sutaria, Dhruvitkumar S; Mégroz, Marianne; Kim, Tae Hwan; Loudon-Hossler, Victoria; Wright, Amy; Jimenez-Nieves, Rossie H; Wallace, Miranda J; Cadet, Keisha C; Jiao, Yuanyuan; Boyce, John D; LoVullo, Eric D; Schweizer, Herbert P; Bonomo, Robert A; Bharatham, Nagakumar; Tsuji, Brian T; Landersdorfer, Cornelia B; Norris, Michael H; Soo Shin, Beom; Louie, Arnold; Balasubramanian, Venkataraman; Lee, Richard E; Drusano, George L; Bulitta, Jürgen B
信号转导
发表日期：2021
文献求助 收藏

Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury

RE-1 沉默转录因子的缺失会加速胰腺损伤引起的外分泌损害

期刊:Cell Death & Disease
影响因子:8.1
doi:10.1038/s41419-020-2269-7
Julie K Bray, Ola A Elgamal, Jinmai Jiang, Lais S Wright, Dhruvitkumar S Sutaria, Mohamed Badawi, Madeline G Borcyk, Xiuli Liu, Kristianna M Fredenburg, Martha L Campbell-Thompson, Thomas D Schmittgen
信号转导
WB
发表日期：2020
文献求助 收藏

First Penicillin-Binding Protein Occupancy Patterns for 15 β-Lactams and β-Lactamase Inhibitors in Mycobacterium abscessus

脓肿分枝杆菌中15种β-内酰胺类抗生素和β-内酰胺酶抑制剂的首次青霉素结合蛋白占位模式

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01956-20
Sayed, Alaa R M; Shah, Nirav R; Basso, Kari B; Kamat, Manasi; Jiao, Yuanyuan; Moya, Bartolome; Sutaria, Dhruvitkumar S; Lang, Yinzhi; Tao, Xun; Liu, Weiguo; Shin, Eunjeong; Zhou, Jieqiang; Werkman, Carolin; Louie, Arnold; Drusano, George L; Bulitta, Jürgen B
发表日期：2020
文献求助 收藏

Comparable Bioavailability and Disposition of Pefloxacin in Patients with Cystic Fibrosis and Healthy Volunteers Assessed via Population Pharmacokinetics

通过群体药代动力学评估培氟沙星在囊性纤维化患者和健康志愿者中的生物利用度和体内分布情况

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics11070323
Bulitta, Jürgen B; Jiao, Yuanyuan; Landersdorfer, Cornelia B; Sutaria, Dhruvitkumar S; Tao, Xun; Shin, Eunjeong; Höhl, Rainer; Holzgrabe, Ulrike; Stephan, Ulrich; Sörgel, Fritz
发表日期：2019
文献求助 收藏