日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Mechanistic Elucidation and Stereochemical Consequences of Alternative Binding of Alkenyl Substrates by Engineered Arylmalonate Decarboxylase

工程化芳基丙二酸脱羧酶对烯基底物选择性结合的机理阐明及立体化学后果

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.5c10721
van der Pol, Elske; Schlatzer, Thomas; Hoffka, Gyula; Di Geronimo, Bruno; Eder, Johannes; Schweiger, Anna K; Karava, Marianna; Gross, Dominik; Fischer, Roland C; Kracher, Daniel; Kazlauskas, Romas; Miyamoto, Kenji; Kamerlin, Shina Caroline Lynn; Breinbauer, Rolf; Kourist, Robert
发表日期：2025
文献求助 收藏

Digging out the Molecular Connections between the Catalytic Mechanism of Human Lysosomal α-Mannosidase and Its Pathophysiology

揭示人溶酶体α-甘露糖苷酶催化机制及其病理生理学之间的分子联系

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.4c02229
Di Geronimo, Bruno; Mandl, Špela; Alonso-Gil, Santiago; Žagrović, Bojan; Reibnegger, Gilbert; Nusshold, Christoph; Sánchez-Murcia, Pedro A
Human
发表日期：2025
文献求助 收藏

A new view of missense mutations in α-mannosidosis using molecular dynamics conformational ensembles.

利用分子动力学构象系综对α-甘露糖苷酶缺乏症中的错义突变进行新的研究

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.70080
Mandl Špela, Di Geronimo Bruno, Alonso-Gil Santiago, Grininger Christoph, George Gibu, Ferstl Ulrika, Herzog Sereina Annik, Žagrović Bojan, Nusshold Christoph, Pavkov-Keller Tea, Sánchez-Murcia Pedro A
免疫/内分泌
发表日期：2025
文献求助 收藏

Using residue interaction networks to understand protein function and evolution and to engineer new proteins

利用残基相互作用网络来理解蛋白质功能和进化，并设计新的蛋白质

期刊:Current Opinion in Structural Biology
影响因子:7
doi:10.1016/j.sbi.2024.102922
Yehorova, Dariia; Di Geronimo, Bruno; Robinson, Michael; Kasson, Peter M; Kamerlin, Shina C L
发表日期：2024
文献求助 收藏

Interference of small compounds and Mg(2+) with dsRNA-binding fluorophores compromises the identification of SARS-CoV-2 RdRp inhibitors

小分子化合物和Mg(2+)对dsRNA结合荧光团的干扰会影响SARS-CoV-2 RdRp抑制剂的鉴定。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-024-78354-x
Llanos, Susana; Di Geronimo, Bruno; Casajús, Ester; Blanco-Romero, Elena; Fernández-Leiro, Rafael; Méndez, Juan
SARS-CoV-2
IF
发表日期：2024
文献求助 收藏

Metformin Impedes Oxidation of LDL In Vitro

二甲双胍在体外抑制低密度脂蛋白的氧化

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics15082111
Rossmann, Christine; Ranz, Cornelia; Kager, Gerd; Ledinski, Gerhard; Koestenberger, Martin; Wonisch, Willibald; Wagner, Thomas; Schwaminger, Sebastian P; Di Geronimo, Bruno; Hrzenjak, Andelko; Hallstöm, Seth; Reibnegger, Gilbert; Cvirn, Gerhard; Paar, Margret
发表日期：2023
文献求助 收藏

Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors

大环化作为实现所需多药理活性的途径。三重PI3K/mTOR/PIM抑制剂的发现

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.1c00412
Martínez-González, Sonia; Alvarez, Rosa M; Martín, José I; García, Ana Belén; Riesco-Fagundo, Concepción; Varela, Carmen; Rodríguez Hergueta, Antonio; González Cantalapiedra, Esther; Albarrán, M I; Gómez-Casero, Elena; Cebriá, Antonio; Aguirre, Enara; Ajenjo, Nuria; Cebrián, David; Di Geronimo, Bruno; Cunningham, Darren; O'Neill, Michael; Dave, Harish P G; Blanco-Aparicio, Carmen; Pastor, Joaquín
mTOR
发表日期：2021
文献求助 收藏

Development of inhibitors of receptor protein tyrosine phosphatase β/ζ (PTPRZ1) as candidates for CNS disorders

开发受体蛋白酪氨酸磷酸酶β/ζ (PTPRZ1) 抑制剂作为中枢神经系统疾病的候选药物

期刊:European Journal of Medicinal Chemistry
影响因子:5.9
doi:10.1016/j.ejmech.2017.11.080
Pastor, Miryam; Fernández-Calle, Rosalía; Di Geronimo, Bruno; Vicente-Rodríguez, Marta; Zapico, José María; Gramage, Esther; Coderch, Claire; Pérez-García, Carmen; Lasek, Amy W; Puchades-Carrasco, Leonor; Pineda-Lucena, Antonio; de Pascual-Teresa, Beatriz; Herradón, Gonzalo; Ramos, Ana
信号转导
TPR
神经科学
发表日期：2018
文献求助 收藏

Pharmacological inhibition of Receptor Protein Tyrosine Phosphatase β/ζ (PTPRZ1) modulates behavioral responses to ethanol

受体蛋白酪氨酸磷酸酶β/ζ (PTPRZ1) 的药理学抑制可调节对乙醇的行为反应。

期刊:Neuropharmacology
影响因子:4.6
doi:10.1016/j.neuropharm.2018.04.027
Fernández-Calle, Rosalía; Vicente-Rodríguez, Marta; Pastor, Miryam; Gramage, Esther; Di Geronimo, Bruno; Zapico, José María; Coderch, Claire; Pérez-García, Carmen; Lasek, Amy W; de Pascual-Teresa, Beatriz; Ramos, Ana; Herradón, Gonzalo
信号转导
TPR
发表日期：2018
文献求助 收藏