DiAntonio Aaron相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Dysregulated lactate metabolism synergizes with ALS genetic risk factors to accelerate motor decline

乳酸代谢紊乱与肌萎缩侧索硬化症（ALS）的遗传风险因素协同作用，加速运动功能衰退。

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0347135

Tendulkar, Shweta; Wu, Tong; Strickland, Amy; Hackett, Amber R; Sato-Yamada, Yurie; Mao, Xianrong; Sasaki, Yo; Milbrandt, Jeffrey; Bloom, A Joseph; DiAntonio, Aaron

发表日期：2026

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Modeling neurodegeneration in the retina and strategies for developing pan-neurodegenerative therapies

视网膜神经退行性疾病建模及泛神经退行性疾病疗法开发策略

期刊:Molecular Neurodegeneration

影响因子:17.5

doi:10.1186/s13024-025-00858-5

Ward, Emily L; Benowitz, Larry; Brunner, Thomas M; Bu, Guojun; Cayouette, Michel; Canto-Soler, Valeria; Dá Mesquita, Sandro; Di Polo, Adriana; DiAntonio, Aaron; Duan, Xin; Goldberg, Jeffrey L; He, Zhigang; Hu, Yang; Liddelow, Shane A; La Torre, Anna; Margeta, Milica; Quintana, Francisco; Shekhar, Karthik; Stevens, Beth; Temple, Sally; Venkatesh, Humsa; Welsbie, Derek; Flanagan, John G

发表日期：2025

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Two cardinal features of ALS, reduced STMN2 and pathogenic TDP-43, synergize to accelerate motor decline in mice.

ALS 的两个主要特征，STMN2 减少和致病性 TDP-43，协同作用加速小鼠的运动能力衰退。

期刊:Experimental Neurology

影响因子:4.2

doi:10.1016/j.expneurol.2024.115068

Krus Kelsey L, Benitez Ana Morales, Strickland Amy, Milbrandt Jeffrey, Bloom A Joseph, DiAntonio Aaron

发表日期：2025

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Suppressing phagocyte activation by overexpressing the phosphatidylserine lipase ABHD12 preserves sarmopathic nerves.

通过过度表达磷脂酰丝氨酸脂肪酶 ABHD12 抑制吞噬细胞活化，可以保护肌肉病变神经

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2025.112626

Dingwall Caitlin B, Sasaki Yo, Strickland Amy, Wu Tong, Summers Daniel W, Bloom A Joseph, DiAntonio Aaron, Milbrandt Jeffrey

细胞生物学

发表日期：2025

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Pmp2+ Schwann Cells Maintain the Survival of Large-Caliber Motor Axons.

Pmp2+ 雪旺细胞维持大口径运动轴突的存活

期刊:Journal of Neuroscience

doi:10.1523/JNEUROSCI.1362-24.2025

Kozlowski Mikolaj M, Strickland Amy, Benitez Ana Morales, Schmidt Robert E, Bloom A Joseph, Milbrandt Jeffrey, DiAntonio Aaron

细胞生物学

发表日期：2025

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SARM1 Inhibition Maintains Axonal Integrity After Rat Sciatic Nerve Transection and Repair.

SARM1抑制可维持大鼠坐骨神经切断和修复后的轴突完整性

期刊:Journal of Hand Surgery-American Volume

影响因子:2.1

doi:10.1016/j.jhsa.2024.12.009

Sachar Ryan, Lee Tony Y, DiAntonio Aaron, Dy Christopher J, Wever Jason, Milbrandt Jeff, Brogan David M

发表日期：2025

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TDP-43 suppression of ATP8A2 cryptic splicing implicates phosphatidylserine-driven neuroinflammation in ALS/FTD.

TDP-43 抑制 ATP8A2 隐蔽剪接表明磷脂酰丝氨酸驱动的神经炎症与 ALS/FTD 有关。

doi:10.1101/2025.11.21.689833

O'Connor James T, Loo Hui Qi, Guo Caiwei, Pickles Sarah, Sundali Shea, Jawahar Vidhya Maheswari, Dickson Dennis W, Bloom A Joseph, Petrucelli Leonard, Gitler Aaron D, Milbrandt Jeffrey, DiAntonio Aaron

Immunology/Inflammation

发表日期：2025

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SARM1 is an essential component of neuronal Parthanatos.

SARM1 是神经元死亡的必要组成部分

doi:10.1101/2025.05.14.654090

Wu Tong, Yuan Liya, Sasaki Yo, Buchser William, Bloom A Joseph, DiAntonio Aaron, Milbrandt Jeffrey

发表日期：2025

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Synergistic Protection of Retinal Ganglion Cells (RGCs) by SARM1 Inactivation with CNTF in a Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy

在非动脉炎性前部缺血性视神经病变啮齿动物模型中，SARM1失活与CNTF对视网膜神经节细胞（RGCs）的协同保护作用

影响因子:5.2

doi:10.3390/cells13030202

Guo, Yan; Mehrabian, Zara; Milbrandt, Jeffrey; DiAntonio, Aaron; Bernstein, Steven L

细胞生物学

发表日期：2024

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The structure of NAD(+) consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations

鲍曼不动杆菌NAD(+)消耗蛋白TIR结构域的结构显示出独特的动力学和构象

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2023.105290

Klontz, Erik; Obi, Juliet O; Wang, Yajing; Glendening, Gabrielle; Carr, Jahid; Tsibouris, Constantine; Buddula, Sahthi; Nallar, Shreeram; Soares, Alexei S; Beckett, Dorothy; Redzic, Jasmina S; Eisenmesser, Elan; Palm, Cheyenne; Schmidt, Katrina; Scudder, Alexis H; Obiorah, Trinity; Essuman, Kow; Milbrandt, Jeffrey; Diantonio, Aaron; Ray, Krishanu; Snyder, Michelle L D; Deredge, Daniel; Snyder, Greg A

发表日期：2023

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