Antagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome
基质细胞信号蛋白CCN3对系统性硬化症和马凡综合征中TGF-β和Wnt介导的纤维蛋白生成具有拮抗作用
期刊:Journal of Investigative Dermatology
影响因子:5.7
doi:10.1038/jid.2010.15
Lemaire, Raphael; Farina, Giuseppina; Bayle, Julie; Dimarzio, Michael; Pendergrass, Sarah A; Milano, Ausra; Perbal, Bernard; Whitfield, Michael L; Lafyatis, Robert
信号转导
Wnt/β-Catenin
基质细胞
系统性硬化症
细胞生物学
免疫/内分泌