The parmodulin NRD-21 is an allosteric inhibitor of PAR1 Gq signaling with improved anti-inflammatory activity and stability
帕莫德林NRD-21是一种PAR1 Gq信号通路的变构抑制剂,具有增强的抗炎活性和稳定性。
期刊:Bioorganic & Medicinal Chemistry
影响因子:3
doi:10.1016/j.bmc.2019.06.043
Gandhi, Disha M; Rosas, Ricardo Jr; Greve, Eric; Kentala, Kaitlin; D-R Diby, N'Guessan; Snyder, Vladyslava A; Stephans, Allison; Yeung, Teresa H W; Subramaniam, Saravanan; DiMilo, Elliot; Kurtenbach, Khia E; Arnold, Leggy A; Weiler, Hartmut; Dockendorff, Chris