Diamond Marc I相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

A quantitative cell-based reporter links TDP-43 aggregation and dysfunction to define pathogenic mechanisms

一种基于细胞的定量报告系统将TDP-43聚集和功能障碍联系起来，从而阐明其致病机制。

期刊:PLoS Biology

影响因子:7.2

doi:10.1371/journal.pbio.3003662

Mamede, Lohany Dias; Hu, Miwei; Vaquer-Alicea, Jaime; Titus, Amanda R; Passos, Patricia M; Lantelme, Erica; French, Rachel L; Kirschner, Paige A; Diamond, Marc I; Miller, Timothy M; Ayala, Yuna M

细胞生物学

发表日期：2026

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Cysteines are critical determinants of spontaneous and seeded tau aggregation in cells

半胱氨酸是细胞内自发性和种子诱导的tau蛋白聚集的关键决定因素。

doi:10.64898/2026.03.12.711133

Jayan, Parvathy; Rastogi, Simran; Bommareddy, Vaibhav; Dashnaw, Chad M; Vaquer-Alicea, Jaime; Nguyen, Binh An; Saelices, Lorena; Shahmoradian, Sarah; White, Charles L 3rd; Diamond, Marc I; Joachimiak, Lukasz A

细胞生物学

发表日期：2026

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High-density brush-shaped polymer lipids reduce anti-PEG antibody binding for repeated administration of mRNA therapeutics

高密度刷状聚合物脂质可减少抗PEG抗体的结合，从而实现mRNA疗法的重复给药。

期刊:Nature Materials

影响因子:38.5

doi:10.1038/s41563-024-02116-3

Xiao, Yufen; Lian, Xizhen; Sun, Yehui; Sung, Yun-Chieh; Vaidya, Amogh; Chen, Zexiang; Gupta, Ankit; Chatterjee, Sumanta; Zheng, Lining; Guerrero, Erick; Wang, Xu; Farbiak, Lukas; Yang, Yangyang; Diamond, Marc I; Leal, Cecilia; McDonald, Jeffrey G; Siegwart, Daniel J

发表日期：2025

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VCP regulates early tau seed amplification via specific cofactors

VCP通过特定辅助因子调控早期tau种子扩增

期刊:Molecular Neurodegeneration

影响因子:17.5

doi:10.1186/s13024-024-00783-z

Batra, Sushobhna; Vaquer-Alicea, Jaime; Valdez, Clarissa; Taylor, Skyler P; Manon, Victor A; Vega, Anthony R; Kashmer, Omar M; Kolay, Sourav; Lemoff, Andrew; Cairns, Nigel J; White, Charles L 3rd; Diamond, Marc I

发表日期：2025

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Functional classification of tauopathy strains reveals the role of protofilament core residues

tau蛋白病菌株的功能分类揭示了原丝核心残基的作用

期刊:Science Advances

影响因子:12.5

doi:10.1126/sciadv.adp5978

Vaquer-Alicea, Jaime; Manon, Victor A; Bommareddy, Vaibhav; Kunach, Peter; Gupta, Ankit; Monistrol, Jim; Perez, Valerie A; Tran, Hung Tri; Saez-Calveras, Nil; Du, Siling; Batra, Sushobhna; Stoddard, Daniel; White, Charles L 3rd; Joachimiak, Lukasz A; Shahmoradian, Sarah H; Diamond, Marc I

发表日期：2025

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Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer's disease and primary age-related tauopathy

伴有tau蛋白病理的特发性震颤的特征性种子在形态上与阿尔茨海默病和原发性年龄相关性tau蛋白病无法区分。

期刊:Acta Neuropathologica

影响因子:9.3

doi:10.1007/s00401-024-02843-6

Saez-Calveras, Nil; Vaquer-Alicea, Jaime; White, Charles L 3rd; Tak, Yogesh; Cosentino, Stephanie; Faust, Phyllis L; Louis, Elan D; Diamond, Marc I

阿尔茨海默症

发表日期：2025

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Plasma glial fibrillary acidic protein as a biomarker of acute focal brain injury after high-intensity focused ultrasound thalamotomy

血浆胶质纤维酸性蛋白作为高强度聚焦超声丘脑切开术后急性局灶性脑损伤的生物标志物

期刊:Brain Communications

影响因子:4.5

doi:10.1093/braincomms/fcaf054

Saez-Calveras, Nil; Asturias, Alexander; Yu, James; Stopschinski, Barbara; Vaquer-Alicea, Jaime; O'Suilleabhain, Padraig; McKenzie, Lauren; Viera, Jeniz; Diamond, Marc I; Shah, Bhavya R

发表日期：2025

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Guam amyotrophic lateral sclerosis/parkinsonism-dementia complex (ALS/PDC) features CTE-like tau seeds in brain and spinal cord

关岛肌萎缩侧索硬化症/帕金森病-痴呆综合征（ALS/PDC）的特征是脑和脊髓中存在类似慢性创伤性脑病（CTE）的tau蛋白种子

doi:10.64898/2025.12.22.696002

Saez-Calveras, Nil; Verheijen, Bert M; Morgan, Nabil; Hill, Elizabeth; Taylor, Skyler; Oyanagi, Kiyomitsu; Kakita, Akiyoshi; Song, Yuyu; Joachimiak, Lukasz A; Vaquer-Alicea, Jaime; Diamond, Marc I; Lu, Ying

发表日期：2025

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Modeling late-onset Alzheimer's disease neuropathology via direct neuronal reprogramming

通过直接神经元重编程模拟晚发性阿尔茨海默病神经病理学

影响因子:45.8

doi:10.1126/science.adl2992

Sun, Zhao; Kwon, Ji-Sun; Ren, Yudong; Chen, Shawei; Walker, Courtney K; Lu, Xinguo; Cates, Kitra; Karahan, Hande; Sviben, Sanja; Fitzpatrick, James A J; Valdez, Clarissa; Houlden, Henry; Karch, Celeste M; Bateman, Randall J; Sato, Chihiro; Mennerick, Steven J; Diamond, Marc I; Kim, Jungsu; Tanzi, Rudolph E; Holtzman, David M; Yoo, Andrew S

阿尔茨海默症

发表日期：2024

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Tau seeding without tauopathy

无tau蛋白病变的tau蛋白播散

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2023.105545

LaCroix, Michael S; Artikis, Efrosini; Hitt, Brian D; Beaver, Joshua D; Estill-Terpack, Sandi-Jo; Gleason, Kelly; Tamminga, Carol A; Evers, Bret M; White, Charles L 3rd; Caughey, Byron; Diamond, Marc I

发表日期：2024

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