日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

AAV immuno-gene therapy platform delivering vectorized cytokines defines a new modality for high-grade glioma treatment

递送载体化细胞因子的AAV免疫基因治疗平台定义了一种治疗高级别胶质瘤的新方法。

Kuwahara, Akela; Fenton, Ethan M; Lovejoy, Chris; Lee, Tian; Wang, Lin; Fogarty, Miko; Jung, Jangham; Guo, Syuan-Ming; Maynard, Lucy H; May, Andrew P; Rossenberg-Hasson, Yael; Clarke, Jennifer L; Diaz, Aaron A; Phillips, Joanna J; Kelly, Lauren; Clément, Nathalie; Paulk, Nicole K

Longitudinal multimodal profiling of IDH-wildtype glioblastoma reveals the molecular evolution and cellular phenotypes underlying prognostically different treatment responses

对IDH野生型胶质母细胞瘤进行纵向多模态分析,揭示了预后不同的治疗反应背后的分子演变和细胞表型。

Lucas, Calixto-Hope G; Al-Adli, Nadeem N; Young, Jacob S; Gupta, Rohit; Morshed, Ramin A; Wu, Jasper; Ravindranathan, Ajay; Shai, Anny; Oberheim Bush, Nancy Ann; Taylor, Jennie W; de Groot, John; Villanueva-Meyer, Javier E; Pekmezci, Melike; Perry, Arie; Bollen, Andrew W; Theodosopoulos, Philip V; Aghi, Manish K; Chang, Edward F; Hervey-Jumper, Shawn L; Raleigh, David R; Molinaro, Annette M; Costello, Joseph F; Diaz, Aaron A; Clarke, Jennifer L; Butowski, Nicholas A; Phillips, Joanna J; Chang, Susan M; Berger, Mitchel S; Solomon, David A

Measles Oncolytic Virus as an Immunotherapy for Recurrent/Refractory Pediatric Medulloblastoma and Atypical Teratoid/Rhabdoid Tumor: Results from PNOC005.

麻疹溶瘤病毒作为复发/难治性儿童髓母细胞瘤和非典型畸胎瘤/横纹肌样瘤的免疫疗法:PNOC005 的结果

Yu Bohyeon, Kline Cassie, Hoare Owen, Jung Jangham, Knowles Truman, Ranavaya Aeesha, Minturn Jane, Banerjee Anu, Leary Sarah, Crotty Erin, Abdelbaki Mohamed, Whipple Nicholas, Goldman Stewart, Margol Ashley, Bhatia Aashim, Dababo Nour, George Elizabeth, Nabavizadeh Ali, Pampaloni Miguel H, Inagaki Akihito, Collins Sara, Chuntova Pavlina, Barcova Maria, Patel Trishna S, Phillips Joanna, Prados Michael, Molinaro Annette, Gupta Nalin, Raffel Corey, Cole Kristina, Kasahara Noriyuki, Diaz Aaron A, Mueller Sabine

A single-cell atlas of glioblastoma evolution under therapy reveals cell-intrinsic and cell-extrinsic therapeutic targets

胶质母细胞瘤治疗过程中单细胞演变图谱揭示了细胞内在和细胞外在的治疗靶点

Wang, Lin; Jung, Jangham; Babikir, Husam; Shamardani, Karin; Jain, Saket; Feng, Xi; Gupta, Nalin; Rosi, Susanna; Chang, Susan; Raleigh, David; Solomon, David; Phillips, Joanna J; Diaz, Aaron A

Loss of ATRX suppresses anti-tumor immunity

ATRX 的缺失会抑制抗肿瘤免疫力。

Diaz, Aaron A

TIGIT and PD-1 Immune Checkpoint Pathways Are Associated With Patient Outcome and Anti-Tumor Immunity in Glioblastoma

TIGIT 和 PD-1 免疫检查点通路与胶质母细胞瘤患者的预后和抗肿瘤免疫相关

Raphael, Itay; Kumar, Rajeev; McCarl, Lauren H; Shoger, Karsen; Wang, Lin; Sandlesh, Poorva; Sneiderman, Chaim T; Allen, Jordan; Zhai, Shuyan; Campagna, Marissa Lynn; Foster, Alexandra; Bruno, Tullia C; Agnihotri, Sameer; Hu, Baoli; Castro, Brandyn A; Lieberman, Frank S; Broniscer, Alberto; Diaz, Aaron A; Amankulor, Nduka M; Rajasundaram, Dhivyaa; Pollack, Ian F; Kohanbash, Gary

Exosomal PD-L1 induces immunosuppressive nonclassical monocytes

外泌体PD-L1诱导免疫抑制性非经典单核细胞

Diaz, Aaron A

The Phenotypes of Proliferating Glioblastoma Cells Reside on a Single Axis of Variation

增殖性胶质母细胞瘤细胞的表型位于单一变异轴上

Wang, Lin; Babikir, Husam; Müller, Sören; Yagnik, Garima; Shamardani, Karin; Catalan, Francisca; Kohanbash, Gary; Alvarado, Beatriz; Di Lullo, Elizabeth; Kriegstein, Arnold; Shah, Sumedh; Wadhwa, Harsh; Chang, Susan M; Phillips, Joanna J; Aghi, Manish K; Diaz, Aaron A