日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lipid Composition Drastically Alters Tau-Membrane Interaction: Implications for Alzheimer's Disease

脂质组成显著改变Tau蛋白与细胞膜的相互作用:对阿尔茨海默病的影响

Wu, Annan; Kandel, Nabin; Li, Shanlong; Enoki, Thais A; Hewes, Kristen; Palumbo, Jacob; Buttaci, Mason; Jones, Kristina; Xia, Ke; Zhao, Jing; Dick, Robert A; Belfort, Georges; Chen, Jianhan; Forth, Scott; Wang, Chunyu

Structural Basis of Polypurine Track Strand Displacement by HIV-1 Reverse Transcriptase

HIV-1逆转录酶对多嘌呤链置换的结构基础

Wen, Xin; Lee, Rachel; Muppalla, Sri Dhanya; McFadden, William M; Kirby, Karen A; Dick, Robert A; Sarafianos, Stefan G

Lenacapavir prevents production of infectious HIV-1 by abrogating immature virus assembly

利那卡帕韦通过抑制未成熟病毒的组装来阻止具有感染性的HIV-1的产生。

Ricaña, Clifton L; Brancato, Savannah G; Highland, Carolyn M; Ekbataniamiri, Fatemeh; Ambrus, Krisztina; Rey, Juan S; Faerch, Mia; Torbett, Bruce E; Perilla, Juan R; Dick, Robert A

Damaging the conical morphology of HIV-1 capsid by targeting the FG-binding pocket and disfavoring pentameric subunits needed for core closure

通过靶向FG结合口袋破坏HIV-1衣壳的锥形形态,并抑制核心闭合所需的五聚体亚基的形成。

McFadden, William M; Kirby, Karen A; Lorson, Zachary C; Wang, Lei; Highland, Carolyn M; Harvey, Sophie R; Brancato, Savannah; Emanuelli Castaner, Andres; Du, Haijuan; Wysocki, Vicki H; Wang, Zhengqiang; Dick, Robert A; Sarafianos, Stefan G

The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation.

保守的 HIV-1 间隔肽 2 触发基质晶格成熟

Stacey James C V, Hrebík Dominik, Nand Elizabeth, Shetty Snehith Dyavari, Qu Kun, Boicu Marius, Anders-Össwein Maria, Uchil Pradeep D, Dick Robert A, Mothes Walther, Kräusslich Hans-Georg, Müller Barbara, Briggs John A G

Translocation of HIV capsid core through the Nuclear Pore Complex by affinity gradient

HIV衣壳核心通过亲和梯度穿过核孔复合体进行转运

Melčák, Ivo; Slack, Ryan L; Lorson, Zachary C; Emanuelli Castaner, Andres; Ambrus, Krisztina; Winkjer, Jonathan S; Kirby, Karen A; Dick, Robert A; Sarafianos, Stefan G

Considerations for capsid-targeting antiretrovirals in pre-exposure prophylaxis

暴露前预防中针对衣壳的抗逆转录病毒药物的考虑因素

McFadden, William M; Faerch, Mia; Kirby, Karen A; Dick, Robert A; Torbett, Bruce E; Sarafianos, Stefan G

Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding

HIV-1衣壳中的两个结构开关调节衣壳曲率和宿主因子结合

Stacey, James C V; Tan, Aaron; Lu, John M; James, Leo C; Dick, Robert A; Briggs, John A G

Inositol Phosphates and Retroviral Assembly: A Cellular Perspective

肌醇磷酸酯与逆转录病毒组装:细胞视角

Ricaña, Clifton L; Dick, Robert A

Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis

HIV-1衣壳对代谢物的通透性调节病毒DNA合成

Xu, Chaoyi; Fischer, Douglas K; Rankovic, Sanela; Li, Wen; Dick, Robert A; Runge, Brent; Zadorozhnyi, Roman; Ahn, Jinwoo; Aiken, Christopher; Polenova, Tatyana; Engelman, Alan N; Ambrose, Zandrea; Rousso, Itay; Perilla, Juan R