日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CTx001 for Geographic Atrophy: A Gene Therapy Expressing Soluble, Truncated Complement Receptor 1 (Mini-CR1)

CTx001 用于治疗地图状萎缩:一种表达可溶性截短补体受体 1 (Mini-CR1) 的基因疗法

Rathi, Sonika; Didangelos, Athanasios; Pisarenka, Sofiya; Green, Rachel; Zafeiri, Stamatia; Emery-Billcliff, Peter; Patel, Nakul; Whalley, Pamela; Zamiri, Parisa; Tilakaratna, Viranga; Szula, Ewa; Hasan, Rafiq; Munye, Mustafa M; Unwin, Richard D; Bishop, Paul N; Keefe, Dennis; Clark, Simon J

From expression footprints to causal pathways: contextualizing large signaling networks with CARNIVAL

从表达足迹到因果通路:利用 CARNIVAL 对大型信号网络进行上下文分析

Liu, Anika; Trairatphisan, Panuwat; Gjerga, Enio; Didangelos, Athanasios; Barratt, Jonathan; Saez-Rodriguez, Julio

Connective tissue growth factor contributes to joint homeostasis and osteoarthritis severity by controlling the matrix sequestration and activation of latent TGFβ

结缔组织生长因子通过控制基质隔离和激活潜伏的TGFβ,影响关节稳态和骨关节炎的严重程度。

Tang, Xiaodi; Muhammad, Hayat; McLean, Celia; Miotla-Zarebska, Jadwiga; Fleming, Jacob; Didangelos, Athanasios; Önnerfjord, Patrik; Leask, Andrew; Saklatvala, Jeremy; Vincent, Tonia L

Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury

免疫逃逸基因开关可实现脊髓损伤后软骨素酶的调控性递送

Burnside, Emily R; De Winter, Fred; Didangelos, Athanasios; James, Nicholas D; Andreica, Elena-Cristina; Layard-Horsfall, Hugo; Muir, Elizabeth M; Verhaagen, Joost; Bradbury, Elizabeth J

Combined Transcriptomics, Proteomics and Bioinformatics Identify Drug Targets in Spinal Cord Injury

结合转录组学、蛋白质组学和生物信息学方法,鉴定脊髓损伤的药物靶点

Tica, Jure; Bradbury, Elizabeth J; Didangelos, Athanasios

Comparative Transcriptomics of Rat and Axolotl After Spinal Cord Injury Dissects Differences and Similarities in Inflammatory and Matrix Remodeling Gene Expression Patterns

大鼠和墨西哥钝口螈脊髓损伤后转录组学比较分析揭示炎症和基质重塑基因表达模式的异同

Tica, Jure; Didangelos, Athanasios

The Expression of Inflammatory Mediators in Bladder Pain Syndrome

膀胱疼痛综合征中炎症介质的表达

Offiah, Ifeoma; Didangelos, Athanasios; Dawes, John; Cartwright, Rufus; Khullar, Vik; Bradbury, Elizabeth J; O'Sullivan, Suzanne; Williams, Dic; Chessell, Iain P; Pallas, Kenny; Graham, Gerry; O'Reilly, Barry A; McMahon, Stephen B

The role of G-protein receptor 84 in experimental neuropathic pain

G蛋白偶联受体84在实验性神经性疼痛中的作用

Nicol, Louise S C; Dawes, John M; La Russa, Federica; Didangelos, Athanasios; Clark, Anna K; Gentry, Clive; Grist, John; Davies, John B; Malcangio, Marzia; McMahon, Stephen B

Regulation of IL-10 by chondroitinase ABC promotes a distinct immune response following spinal cord injury

软骨素酶ABC对IL-10的调节促进脊髓损伤后独特的免疫反应

Didangelos, Athanasios; Iberl, Michaela; Vinsland, Elin; Bartus, Katalin; Bradbury, Elizabeth J

Large-scale chondroitin sulfate proteoglycan digestion with chondroitinase gene therapy leads to reduced pathology and modulates macrophage phenotype following spinal cord contusion injury.

利用软骨素酶基因疗法进行大规模硫酸软骨素蛋白聚糖消化,可减少脊髓挫伤后的病理变化并调节巨噬细胞表型

Bartus Katalin, James Nicholas D, Didangelos Athanasios, Bosch Karen D, Verhaagen Joost, Yáñez-Muñoz Rafael J, Rogers John H, Schneider Bernard L, Muir Elizabeth M, Bradbury Elizabeth J