日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

microRNA-132 attenuates inflammation in induced pluripotent stem cell-derived microglia from Alzheimer's disease patients

microRNA-132可减轻阿尔茨海默病患者诱导多能干细胞衍生的小胶质细胞的炎症反应

期刊:Acta Neuropathologica Communications
影响因子:5.7
doi:10.1186/s40478-026-02228-8
Penning, Amber; Snoeck, Sarah; Ormaechea, Olmo Ruiz; Ayyildiz, Dilara; Polzer, Oliver; Buitrago-Arango, Martin; Capobianco, Raffaella; de Winter, Fred; Balusu, Sriram; Verhaagen, Joost; Fitzsimons, Carlos P; d'Ydewalle, Constantin; Lucassen, Paul J; Moechars, Dieder; Zhou, Lujia; Salta, Evgenia
胶质细胞
炎症
细胞生物学
炎症/感染
阿尔茨海默症
干细胞
发育与干细胞
发表日期：2026
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A Potential Pitfall in the Interpretation of Microscope-Integrated Fluorescence Angiography: The Center-Periphery Effect

显微镜集成荧光血管造影图像解读中的潜在陷阱：中心-外周效应

期刊:Medical Sciences
影响因子:4.4
doi:10.3390/medsci13020054
Stolk, Dieder; Bloemen, Paul; van den Elzen, Richard Martin; de Bruin, Martijn; Driessen, Caroline
IF
发表日期：2025
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Absence of Uptake and Prion-Like Spreading of Alpha-Synuclein and Tau After Intravitreal Injection of Preformed Fibrils

玻璃体内注射预形成的纤维后，α-突触核蛋白和 Tau 不被吸收，也不发生朊病毒样扩散

期刊:Frontiers in Aging Neuroscience
影响因子:4.1
doi:10.3389/fnagi.2020.614587
Lien Veys, Jessie Van Houcke, Jeroen Aerts, Sophie Van Pottelberge, Michel Mahieu, Audrey Coens, Ronald Melki, Dieder Moechars, Louis De Muynck, Lies De Groef
微生物学
发表日期：2021
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PIKfyve activity is required for lysosomal trafficking of tau aggregates and tau seeding

PIKfyve 活性是溶酶体运输 tau 聚集体和 tau 接种所必需的

期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1016/j.jbc.2021.100636
Alberto Carpinteiro Soares, Andreia Ferreira, Jonas Mariën, Charlotte Delay, Edward Lee, John Q Trojanowski, Dieder Moechars, Wim Annaert, Louis De Muynck
信号转导
发表日期：2021
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BACE2 distribution in major brain cell types and identification of novel substrates

BACE2 在主要脑细胞类型中的分布及新底物的识别

期刊:Life Science Alliance
影响因子:3.3
doi:10.26508/lsa.201800026
Iryna Voytyuk, Stephan A Mueller, Julia Herber, An Snellinx, Dieder Moechars, Geert van Loo, Stefan F Lichtenthaler, Bart De Strooper
细胞生物学
其它细胞
WB
发表日期：2018
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Developmental Expression of 4-Repeat-Tau Induces Neuronal Aneuploidy in Drosophila Tauopathy Models

4-重复Tau蛋白的发育表达诱导果蝇Tau蛋白病模型中的神经元非整倍体

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/srep40764
Malmanche, Nicolas; Dourlen, Pierre; Gistelinck, Marc; Demiautte, Florie; Link, Nichole; Dupont, Cloé; Vanden Broeck, Lies; Werkmeister, Elisabeth; Amouyel, Philippe; Bongiovanni, Antonino; Bauderlique, Hélène; Moechars, Dieder; Royou, Anne; Bellen, Hugo J; Lafont, Frank; Callaerts, Patrick; Lambert, Jean-Charles; Dermaut, Bart
Drosophila
发育与干细胞
神经科学
发表日期：2017
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BACE1 Dynamics Upon Inhibition with a BACE Inhibitor and Correlation to Downstream Alzheimer's Disease Markers in Elderly Healthy Participants

使用 BACE 抑制剂抑制 BACE1 后其动态变化及其与老年健康参与者下游阿尔茨海默病标志物的相关性

期刊:Journal of Alzheimers Disease
影响因子:3.1
doi:10.3233/JAD-160829
Timmers, Maarten; Barão, Soraia; Van Broeck, Bianca; Tesseur, Ina; Slemmon, John; De Waepenaert, Katja; Bogert, Jennifer; Shaw, Leslie M; Engelborghs, Sebastiaan; Moechars, Dieder; Mercken, Marc; Van Nueten, Luc; Tritsmans, Luc; de Strooper, Bart; Streffer, Johannes Rolf
BACE1
阿尔茨海默症
发表日期：2017
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Profiling the dynamics of CSF and plasma Aβ reduction after treatment with JNJ-54861911, a potent oral BACE inhibitor

分析强效口服BACE抑制剂JNJ-54861911治疗后脑脊液和血浆Aβ减少的动态变化

期刊:Alzheimer's and Dementia: Translational Research and Clinical Interventions
影响因子:6.8
doi:10.1016/j.trci.2016.08.001
Timmers, Maarten; Van Broeck, Bianca; Ramael, Steven; Slemmon, John; De Waepenaert, Katja; Russu, Alberto; Bogert, Jennifer; Stieltjes, Hans; Shaw, Leslie M; Engelborghs, Sebastiaan; Moechars, Dieder; Mercken, Marc; Liu, Enchi; Sinha, Vikash; Kemp, John; Van Nueten, Luc; Tritsmans, Luc; Streffer, Johannes Rolf
神经科学
发表日期：2016
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Inositol-related gene knockouts mimic lithium's effect on mitochondrial function

肌醇相关基因敲除模拟了锂对线粒体功能的影响

期刊:Neuropsychopharmacology
影响因子:7.1
doi:10.1038/npp.2013.194
Toker, Lilach; Bersudsky, Yuly; Plaschkes, Inbar; Chalifa-Caspi, Vered; Berry, Gerard T; Buccafusca, Roberto; Moechars, Dieder; Belmaker, R H; Agam, Galila
线粒体
发表日期：2014
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Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice

增加脑蛋白 O-GlcNAc 化可减轻 Tau.P301L 小鼠的呼吸缺陷和死亡率

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0084442
Peter Borghgraef, Clément Menuet, Clara Theunis, Justin V Louis, Herman Devijver, Hervé Maurin, Caroline Smet-Nocca, Guy Lippens, Gerard Hilaire, Harrie Gijsen, Dieder Moechars, Fred Van Leuven
信号转导
发表日期：2013
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