日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Comparative whole-genome analyses of articular chondrocytes and skin fibroblasts reveal distinct genome instability landscapes in mesenchymal cell types

对关节软骨细胞和皮肤成纤维细胞的比较全基因组分析揭示了间充质细胞类型中不同的基因组不稳定性特征。

Sauty, Safia Mahabub; Shine, Jacqueline; Bostan, Hamed; Li, Jian-Liang; Mieczkowski, Piotr A; Loeser, Richard F; Diekman, Brian O; Gordenin, Dmitry A

Response eQTLs, chromatin accessibility, and 3D chromatin structure in chondrocytes provide mechanistic insight into osteoarthritis risk

软骨细胞中的响应eQTL、染色质可及性和3D染色质结构为骨关节炎风险提供了机制方面的见解。

Kramer, Nicole E; Byun, Seyoun; Coryell, Philip; D'Costa, Susan; Thulson, Eliza; Kim, HyunAh; Parkus, Sylvie M; Bond, Marielle L; Klein, Emma R; Shine, Jacqueline; Chubinskaya, Susanna; Love, Michael I; Mohlke, Karen L; Diekman, Brian O; Loeser, Richard F; Phanstiel, Douglas H

Multiplexed single-cell imaging reveals diverging subpopulations with distinct senescence phenotypes during long-term senescence induction

多重单细胞成像揭示了长期衰老诱导过程中具有不同衰老表型的分化亚群

Sessions, Garrett A; Loops, Madeline V; Diekman, Brian O; Purvis, Jeremy E

Biomarkers of aging as it relates osteoarthritis: we can't improve what we can't measure

与骨关节炎相关的衰老生物标志物:我们无法改善无法衡量的东西。

Diekman, Brian O; Hsueh, Ming-Feng

DNA Damage and Cellular Senescence in Osteoarthritis: An Unexpected Role for Interferon Regulatory Factor 1 in Chondrocyte DNA Repair

骨关节炎中的DNA损伤和细胞衰老:干扰素调节因子1在软骨细胞DNA修复中的意外作用

Diekman, Brian O; Loeser, Richard F

Aging and the emerging role of cellular senescence in osteoarthritis

衰老及细胞衰老在骨关节炎中的新兴作用

Diekman, Brian O; Loeser, Richard F

Use of a novel magnetically actuated compression system to study the temporal dynamics of axial and lateral strain in human osteochondral plugs

利用新型磁致压缩系统研究人骨软骨栓轴向和横向应变的时间动态变化

Rich, Matthew J; Burnash, Sarah; Krishnan, Rohan R; Chubinskaya, Susan; Loeser, Richard F; Polacheck, William J; Diekman, Brian O

Epigenetics as a mediator of genetic risk in osteoarthritis: role during development, homeostasis, aging, and disease progression

表观遗传学作为骨关节炎遗传风险的介质:在发育、稳态、衰老和疾病进展中的作用

Richard, Daniel; Capellini, Terence D; Diekman, Brian O

Mechanisms and therapeutic implications of cellular senescence in osteoarthritis

骨关节炎中细胞衰老的机制和治疗意义

Coryell, Philip R; Diekman, Brian O; Loeser, Richard F

Microfluidics for the study of mechanotransduction

微流控技术在机械转导研究中的应用

Griffith, Christian M; Huang, Stephanie A; Cho, Crescentia; Khare, Tanmay M; Rich, Matthew; Lee, Gi-Hun; Ligler, Frances S; Diekman, Brian O; Polacheck, William J