日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-cell profiling reveals that dynamic lung immune responses distinguish protection from susceptibility to tuberculosis

单细胞分析表明,动态的肺部免疫反应能够区分对结核病的保护作用和易感性。

Duffy, Fergal J; Neal, Maxwell L; Plumlee, Courtney R; Cohen, Sara B; Gern, Benjamin H; Diercks, Alan H; Gerner, Michael Y; Urdahl, Kevin B; Aitchison, John D

Early and opposing neutrophil and CD4 T cell responses shape pulmonary tuberculosis pathology.

早期相反的中性粒细胞和 CD4 T 细胞反应塑造了肺结核的病理

Gern Benjamin H, Klas Josepha M, Foster Kimberly A, Kanagy Molly E, Cohen Sara B, Plumlee Courtney R, Duffy Fergal J, Neal Maxwell L, Halima Mehnaz, Gustin Andrew T, Stull Sylvia M, Wilson Jasmine J, Diercks Alan H, Aderem Alan, Gale Michael Jr, Aitchison John D, Gerner Michael Y, Urdahl Kevin B

c-Myc Inhibits Macrophage Antimycobacterial Response in Mycobacterium tuberculosis Infection

c-Myc抑制结核分枝杆菌感染中巨噬细胞的抗分枝杆菌反应

Sarti, Edoardo; Dollé, Cédric; Wolfensberger, Rebekka; Kusejko, Katharina; Russenberger, Doris; Bredl, Simon; Speck, Roberto F; Greter, Melanie; Rueschoff, Jan H; Boeck, Lucas; Mai, Dat; Jahn, Ana N; Gold, Elizabeth S; Liu, Dong; Diercks, Alan H; Sander, Peter; Olson, Gregory S; Nemeth, Johannes

c-Myc inhibits macrophage antimycobacterial response in Mycobacterium tuberculosis infection.

c-Myc抑制结核分枝杆菌感染中巨噬细胞的抗分枝杆菌反应

Sarti Edoardo, Dollé Cédric, Wolfensberger Rebekka, Kusejko Katharina, Russenberger Doris, Bredl Simon, Speck Roberto F, Greter Melanie, Rueschoff Jan H, Boeck Lucas, Mai Dat, Diercks Alan H, Sander Peter, Olson Gregory S, Nemeth Johannes

Host and pathogen genetic diversity shape vaccine-mediated protection to Mycobacterium tuberculosis

宿主和病原体的遗传多样性影响疫苗介导的对结核分枝杆菌的保护作用

Cohen, Sara B; Plumlee, Courtney R; Engels, Lindsay; Mai, Dat; Murray, Tara A; Jahn, Ana N; Alexander, Bridget; Delahaye, Jared L; Cross, Lauren M; Maciag, Karolina; Schrader, Sam; Durga, Kaitlin; Gold, Elizabeth S; Aderem, Alan; Gerner, Michael Y; Gern, Benjamin H; Diercks, Alan H; Urdahl, Kevin B

Exposure to Mycobacterium remodels alveolar macrophages and the early innate response to Mycobacterium tuberculosis infection

接触结核分枝杆菌会重塑肺泡巨噬细胞以及对结核分枝杆菌感染的早期先天免疫反应。

Mai, Dat; Jahn, Ana; Murray, Tara; Morikubo, Michael; Lim, Pamelia N; Cervantes, Maritza M; Pham, Linh K; Nemeth, Johannes; Urdahl, Kevin; Diercks, Alan H; Aderem, Alan; Rothchild, Alissa C

PPARα exacerbates necroptosis, leading to increased mortality in postinfluenza bacterial superinfection

PPARα加剧坏死性凋亡,导致流感后细菌继发感染的死亡率增加。

Tam, Vincent C; Suen, Rosa; Treuting, Piper M; Armando, Aaron; Lucarelli, Ronald; Gorrochotegui-Escalante, Norma; Diercks, Alan H; Quehenberger, Oswald; Dennis, Edward A; Aderem, Alan; Gold, Elizabeth S

Contained Mycobacterium tuberculosis infection induces concomitant and heterologous protection

控制性结核分枝杆菌感染可诱导伴随性异源保护。

Nemeth, Johannes; Olson, Gregory S; Rothchild, Alissa C; Jahn, Ana N; Mai, Dat; Duffy, Fergal J; Delahaye, Jared L; Srivatsan, Sanjay; Plumlee, Courtney R; Urdahl, Kevin B; Gold, Elizabeth S; Aderem, Alan; Diercks, Alan H

miR-144 attenuates the host response to influenza virus by targeting the TRAF6-IRF7 signaling axis

miR-144通过靶向TRAF6-IRF7信号通路减弱宿主对流感病毒的反应。

Rosenberger, Carrie M; Podyminogin, Rebecca L; Diercks, Alan H; Treuting, Piper M; Peschon, Jacques J; Rodriguez, David; Gundapuneni, Madhumati; Weiss, Mitchell J; Aderem, Alan

Characterization of innate responses to influenza virus infection in a novel lung type I epithelial cell model

利用新型I型肺上皮细胞模型表征流感病毒感染的先天免疫反应

Rosenberger, Carrie M; Podyminogin, Rebecca L; Askovich, Peter S; Navarro, Garnet; Kaiser, Shari M; Sanders, Catherine J; McClaren, Jennifer L; Tam, Vincent C; Dash, Pradyot; Noonan, Jhoanna G; Jones, Bart G; Surman, Sherri L; Peschon, Jacques J; Diercks, Alan H; Hurwitz, Julia L; Doherty, Peter C; Thomas, Paul G; Aderem, Alan