日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

S-phase checkpoint protects from aberrant replication fork processing and degradation.

S期检查点可防止异常复制叉处理和性能下降

Núñez-Martín Iván, Drury Lucy S, Martínez-Jiménez María I, Blanco Luis, Diffley John F X, Aguilera Andrés, Gómez-González Belén

Mechanisms for licensing origins of DNA replication in eukaryotic cells

真核细胞中DNA复制起始点的许可机制

Stillman, Bruce; Diffley, John F X; Iwasa, Janet H

Cell cycle regulation has shaped replication origins in budding yeast

细胞周期调控塑造了出芽酵母的复制起点。

Lim, Chew Theng; Miller, Thomas C R; Tan, Kang Wei; Talele, Saurabh; Early, Anne; East, Philip; Sánchez, Humberto; Dekker, Nynke H; Costa, Alessandro; Diffley, John F X

MCM double hexamer loading visualized with human proteins.

MCM双六聚体加载与人类蛋白质可视化

Weissmann Florian, Greiwe Julia F, Pühringer Thomas, Eastwood Evelyn L, Couves Emma C, Miller Thomas C R, Diffley John F X, Costa Alessandro

Unwinding of a eukaryotic origin of replication visualized by cryo-EM

利用冷冻电镜观察真核生物复制起点的解旋过程

Henrikus, Sarah S; Gross, Marta H; Willhoft, Oliver; Pühringer, Thomas; Lewis, Jacob S; McClure, Allison W; Greiwe, Julia F; Palm, Giacomo; Nans, Andrea; Diffley, John F X; Costa, Alessandro

Author Correction: Unwinding of a eukaryotic origin of replication visualized by cryo-EM

作者更正:冷冻电镜可视化真核生物复制起点的解旋过程

Henrikus, Sarah S; Gross, Marta H; Willhoft, Oliver; Pühringer, Thomas; Lewis, Jacob S; McClure, Allison W; Greiwe, Julia F; Palm, Giacomo; Nans, Andrea; Diffley, John F X; Costa, Alessandro

Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase

Dbf4依赖性激酶选择性磷酸化DNA负载的MCM双六聚体的结构机制

Greiwe, Julia F; Miller, Thomas C R; Locke, Julia; Martino, Fabrizio; Howell, Steven; Schreiber, Anne; Nans, Andrea; Diffley, John F X; Costa, Alessandro

Unchecked nick ligation can promote localized genome re-replication

未经控制的切口连接可促进局部基因组的重新复制。

Johansson, Erik; Diffley, John F X

Author's overview: identifying SARS-CoV-2 antiviral compounds

作者概述:鉴定SARS-CoV-2抗病毒化合物

Diffley, John F X

Cryo-EM structure of a licensed DNA replication origin

已获许可的DNA复制起点的冷冻电镜结构

Abid Ali, Ferdos; Douglas, Max E; Locke, Julia; Pye, Valerie E; Nans, Andrea; Diffley, John F X; Costa, Alessandro