日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Biochemical characterization of xyloglucan galactosyltransferases MUR3 and XLT2 from Spirodela polyrhiza

多根螺菌木葡聚糖半乳糖基转移酶 MUR3 和 XLT2 的生化特性

Corulli, Charles J; Graf, Alexander S; Chapla, Digantkumar; Zhang, Liang; Ziegler, Samantha J; Byrnes, James; Bomble, Yannick J; Moremen, Kelley W; Urbanowicz, Breeanna R; Prabhakar, Pradeep K

Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors in Non-diabetic Conditions Beyond Heart Failure and Chronic Kidney Disease: Emerging Evidence, Mechanisms, and Practical Considerations

钠-葡萄糖协同转运蛋白2 (SGLT2) 抑制剂在心力衰竭和慢性肾病以外的非糖尿病疾病中的应用:新的证据、机制和实践考虑

Patel, Digantkumar; Patel, Tejas

Siglec-targeted liposomes to identify sialoglycans present on fungal pathogens.

利用 Siglec 靶向脂质体识别真菌病原体上存在的唾液酸聚糖

Ambati Suresh, Choudhury Quanita J, Peter Jesse Ann, Moremen Kelley W, Chapla Digantkumar Gopaldas, Lewis Zachary A, Lin Xiaorong, Meagher Richard B

Charge matters: how flanking substrate charge modulates O-glycan Core elongation

电荷很重要:侧翼底物电荷如何调节O-聚糖核心的延伸

Ballard, Collin J; Smutny, Matthew R; Chau, Lam D; Wong, Collin K; Aharoni, Haley M; Lee, Hana K; Chapla, Digantkumar G; Hurtado-Guerrero, Ramon; Moremen, Kelley W; Gerken, Thomas A

Mucin-type O-glycans regulate proteoglycan stability and chondrocyte maturation

黏蛋白型O-聚糖调节蛋白聚糖稳定性及软骨细胞成熟

Dong, Xiaolin; Bedillion, Sydney; Gosnell, Kaleigh E; Zhao, Peng; Basu, Amrita; Suryadevara, Kavya; Chapla, Digantkumar; Wells, Lance; Weiss, Ryan J

Biochemical and structural characterization of glycosyltransferase family 61 proteins reveal a key determinant of sugar donor specificity

糖基转移酶61家族蛋白的生化和结构表征揭示了糖供体特异性的关键决定因素

Wang, Hsin-Tzu; Pereira, Jose Henrique; DeGiovanni, Andy M; Prabhakar, Pradeep Kumar; Chapla, Digantkumar; Moremen, Kelley W; Urbanowicz, Breeanna R; Adams, Paul D; Scheller, Henrik V

Enforced E-selectin ligand installation enhances homing and efficacy of adoptively transferred T cells.

强制安装 E-选择素配体可增强过继转移的 T 细胞的归巢能力和疗效

Hou Yingqin, Ye Jinfeng, Qin Ke, Cui Leigh-Ann, Chung Shereen, Chapla Digantkumar Gopaldas, Wang Wenjian, Shi Yujie, Chen Mingkuan, Moremen Kelley W, Sackstein Robert, Wu Peng

Integrated chemoenzymatic synthesis of a comprehensive sulfated ganglioside glycan library to decipher functional sulfoglycomics and sialoglycomics

利用化学酶法合成全面的硫酸化神经节苷脂聚糖库,以解析功能性硫酸化糖组学和唾液酸糖组学。

Xu, Zhuojia; Liu, Yating; Liu, Jialin; Ma, Wenjing; Zhang, Zhumin; Chapla, Digantkumar G; Wen, Liuqing; Moremen, Kelley W; Yi, Wen; Li, Tiehai

A Biomimetic Synthetic Strategy Can Provide Keratan Sulfate I and II Oligosaccharides with Diverse Fucosylation and Sulfation Patterns

仿生合成策略可提供具有多种岩藻糖基化和硫酸化模式的硫酸角质素I和II寡糖

Wu, Yunfei; Bosman, Gerlof P; Chapla, Digantkumar; Huang, Chin; Moremen, Kelley W; de Vries, Robert P; Boons, Geert-Jan

Chemoenzymatic Synthesis of Sulfated N-Glycans Recognized by Siglecs and Other Glycan-Binding Proteins

Siglecs 和其他聚糖结合蛋白识别的硫酸化 N-聚糖的化学酶合成

Kun Huang, Eleanor E Bashian, Guanghui Zong, Corwin M Nycholat, Ryan McBride, Margaryta Gomozkova, Shengyang Wang, Chin Huang, Digantkumar G Chapla, Edward N Schmidt, Matthew Macauley, Kelley W Moremen, James C Paulson, Lai-Xi Wang