日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epigenetic tuning of PD-1 expression improves exhausted T cell function and viral control

PD-1表达的表观遗传调控可改善耗竭T细胞的功能和病毒控制。

Sarah A Weiss,Amy Y Huang,Megan E Fung,Daniela Martinez,Alex C Y Chen,Thomas J LaSalle,Brian C Miller,Christopher D Scharer,Mudra Hegde,Thao H Nguyen,Jared H Rowe,Jossef F Osborn,Dillon G Patterson,Natalia Sifnugel,C Mei-An Nolan,Richard A Davidson,Marc A Schwartz,Alexander P R Bally,Dennis K Neeld,Martin W LaFleur,Jeremy M Boss,John G Doench,W Nicholas Haining,Arlene H Sharpe,Debattama R Sen

In Vivo CRISPR Screening Reveals CHD7 as a Positive Regulator of Short-lived Effector Cells

体内 CRISPR 筛选揭示 CHD7 是短寿命效应细胞的正向调节因子

Martin W LaFleur ,Jasmin M D'Andrea ,Dillon G Patterson ,Ivy S L Streeter ,Matthew A Coxe ,Jossef F Osborn ,Lauren E Milling ,Qin Tjokrosurjo ,Jacob E Gillis ,Thao H Nguyen ,Marc A Schwartz ,Nir Hacohen ,John G Doench ,Arlene H Sharpe

Single-cell profiling reveals unique features of diabetogenic T cells in anti-PD-1-induced type 1 diabetes mice

单细胞分析揭示抗 PD-1 诱导的 1 型糖尿病小鼠中致糖尿病 T 细胞的独特特征

Jenna L Collier, Kristen E Pauken, Catherine A A Lee, Dillon G Patterson, Samuel C Markson, Thomas S Conway, Megan E Fung, Joshua A France, Kyla N Mucciarone, Christine G Lian, George F Murphy, Arlene H Sharpe

CRISPR/Cas9 editing reveals IRF8 regulated gene signatures restraining plasmablast differentiation

CRISPR/Cas9基因编辑揭示了IRF8调控的基因特征抑制浆细胞分化

Zhihong Zuo ,Anna K Kania ,Dillon G Patterson ,Sakeenah L Hicks ,Jeffrey Maurer ,Mansi Gupta ,Jeremy M Boss ,Christopher D Scharer

H3K27me3 Demethylase UTX Restrains Plasma Cell Formation

H3K27me3去甲基化酶UTX抑制浆细胞形成

Anna K Kania ,Madeline J Price ,Lou-Ella George-Alexander ,Dillon G Patterson ,Sakeenah L Hicks ,Christopher D Scharer ,Jeremy M Boss

The Murine MHC Class II Super Enhancer IA/IE-SE Contains a Functionally Redundant CTCF-Binding Component and a Novel Element Critical for Maximal Expression

小鼠MHC II类超级增强子IA/IE-SE包含一个功能冗余的CTCF结合组分和一个对最大表达至关重要的新型元件

Parimal Majumder ,Joshua T Lee ,Benjamin G Barwick ,Dillon G Patterson ,Alexander P R Bally ,Christopher D Scharer ,Jeremy M Boss

An IRF4-MYC-mTORC1 Integrated Pathway Controls Cell Growth and the Proliferative Capacity of Activated B Cells during B Cell Differentiation In Vivo

IRF4-MYC-mTORC1整合通路在体内B细胞分化过程中控制细胞生长和活化B细胞的增殖能力

Dillon G Patterson ,Anna K Kania ,Madeline J Price ,James R Rose ,Christopher D Scharer ,Jeremy M Boss

Antibody-secreting cell destiny emerges during the initial stages of B-cell activation

抗体分泌细胞的命运在B细胞活化的初始阶段形成。

Christopher D Scharer # ,Dillon G Patterson # ,Tian Mi ,Madeline J Price ,Sakeenah L Hicks ,Jeremy M Boss

Transcriptomic and epigenomic dynamics associated with development of human iPSC-derived GABAergic interneurons

与人类 iPSC 衍生的 GABA 能中间神经元发育相关的转录组和表观基因组动力学

George Andrew S Inglis, Ying Zhou, Dillon G Patterson, Christopher D Scharer, Yanfei Han, Jeremy M Boss, Zhexing Wen, Andrew Escayg

Phosphoinositide 3-Kinase Signaling Can Modulate MHC Class I and II Expression

磷酸肌醇 3-激酶信号可调节 MHC I 类和 II 类表达

Sanjay Chandrasekaran, Maiko Sasaki, Christopher D Scharer, Haydn T Kissick, Dillon G Patterson, Kelly R Magliocca, John T Seykora, Bishu Sapkota, David A Gutman, Lee A Cooper, Gregory B Lesinski, Edmund K Waller, Susan N Thomas, Sergei V Kotenko, Jeremy M Boss, Carlos S Moreno, Robert A Swerlick, B