日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cytoplasmic NAD/H synthesis via NRK1 regulates inflammatory capacity and promotes survival of CD4(+) T cells

胞质NAD/H合成通过NRK1调节炎症能力并促进CD4(+) T细胞的存活。

Stavrou, Victoria; Ali, Myah; Gudgeon, Nancy; Bishop, Emma L; Fulton-Ward, Taylor; Turley, Bethany; Heising, Silke; Mohamed, Sally H; Hain, Sofia; George, Lorna; Deng, Minghao; McCowan, Jack; Sheriff, Lozan; Davies, Scott P; Marzullo, Bryan; Tennant, Daniel A; Doig, Craig L; Bending, David A; Roberts, Ed W; Lavery, Gareth G; Drummond, Rebecca A; Dimeloe, Sarah

Iron deficiency causes aspartate-sensitive dysfunction in CD8+ T cells

缺铁会导致CD8+ T细胞天冬氨酸敏感性功能障碍

Megan R Teh ,Nancy Gudgeon ,Joe N Frost ,Linda V Sinclair ,Alastair L Smith ,Christopher L Millington ,Barbara Kronsteiner ,Jennie Roberts ,Bryan P Marzullo ,Hannah Murray ,Alexandra E Preston ,Victoria Stavrou ,Jan Rehwinkel ,Thomas A Milne ,Daniel A Tennant ,Susanna J Dunachie ,Andrew E Armitage ,Sarah Dimeloe # ,Hal Drakesmith #

mTOR activity and metabolic reprogramming of CD8+ T cells is impaired under hypoxia and within the multiple myeloma bone marrow

在缺氧和多发性骨髓瘤骨髓中,mTOR活性和CD8+ T细胞的代谢重编程均受到损害。

Fulton-Ward, Taylor; Gudgeon, Nancy; Thirlwell, Isaac; Bishop, Emma L; Marzullo, Bryan; Giles, Hannah; McIlroy, Graham; Ferguson, Paul; Kishore, Bhuvan; Rogers, Kate; Alfasi, Nuri; Wong, Timothy; Aytain, Satnam; Tennant, Daniel A; Pratt, Guy; Dimeloe, Sarah

NAD + metabolism and function in innate and adaptive immune cells

NAD+代谢及其在先天性和适应性免疫细胞中的功能

Mann, Rebecca; Stavrou, Victoria; Dimeloe, Sarah

Proteomic analysis reveals dysregulation of peripheral blood neutrophils in patients with Multiple Sclerosis

蛋白质组学分析揭示多发性硬化症患者外周血中性粒细胞功能失调

Katie J Smith ,Zachary Lim ,Sonja Vermeren ,Veronique E Miron ,Sarah Dimeloe ,Donald J Davidson ,Anna Williams ,Emily Gwyer Findlay

Metabolic Characterization of Deceased Donor Kidneys Undergoing Hypothermic Machine Perfusion Before Transplantation Using (13)C-enriched Glucose

利用(13)C标记的葡萄糖对移植前经低温机械灌注的已故供体肾脏进行代谢表征

Patel, Kamlesh; Nath, Jay; Smith, Thomas; Darius, Tom; Thakker, Alpesh; Dimeloe, Sarah; Inston, Nicholas; Ready, Andrew; Ludwig, Christian

Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity

沙门氏菌癌症疗法通过代谢方式破坏肿瘤,但代价是损害T细胞免疫力。

Alastair Copland,Gillian M Mackie,Lisa Scarfe,Elizabeth Jinks,David A J Lecky,Nancy Gudgeon,Riahne McQuade,Masahiro Ono,Manja Barthel,Wolf-Dietrich Hardt,Hiroshi Ohno,Wilma H M Hoevenaar,Sarah Dimeloe,David Bending,Kendle M Maslowski

The glutamate/aspartate transporter EAAT1 is crucial for T-cell acute lymphoblastic leukemia proliferation and survival

谷氨酸/天冬氨酸转运蛋白EAAT1对T细胞急性淋巴细胞白血病的增殖和存活至关重要。

Stanulović, Vesna S; Al Omair, Shorog; Reed, Michelle A C; Roberts, Jennie; Potluri, Sandeep; Fulton-Ward, Taylor; Gudgeon, Nancy; Bishop, Emma L; Roels, Juliette; Perry, Tracey A; Sarkar, Sovan; Pratt, Guy; Taghon, Tom; Dimeloe, Sarah; Günther, Ulrich L; Ludwig, Christian; Hoogenkamp, Maarten

Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity

卡格列净通过自身免疫中的代谢抑制损害 T 细胞效应功能

Benjamin J Jenkins, Julianna Blagih, Fernando M Ponce-Garcia, Mary Canavan, Nancy Gudgeon, Simon Eastham, David Hill, Megan M Hanlon, Eric H Ma, Emma L Bishop, April Rees, James G Cronin, Elizabeth C Jury, Sarah K Dimeloe, Douglas J Veale, Catherine A Thornton, Karen H Vousden, David K Finlay, Ursul

Uptake of long-chain fatty acids from the bone marrow suppresses CD8+ T-cell metabolism and function in multiple myeloma

骨髓中长链脂肪酸的摄取会抑制多发性骨髓瘤中 CD8+ T 细胞的代谢和功能。

Nancy Gudgeon ,Hannah Giles ,Emma L Bishop ,Taylor Fulton-Ward ,Cristina Escribano-Gonzalez ,Haydn Munford ,Anna James-Bott ,Kane Foster ,Farheen Karim ,Dedunu Jayawardana ,Ansar Mahmood ,Adam P Cribbs ,Daniel A Tennant ,Supratik Basu ,Guy Pratt ,Sarah Dimeloe